总统特朗普的COVID-19该怎么治?REGN-COV2抗体“鸡尾酒疗法”

2020-10-03 Allan MedSci原创

REGN-COV2是两种单克隆抗体的混合物(REGN10933和REGN10987)。

Regeneron Pharmaceuticals今天证实,正如白宫新闻秘书宣布的那样,在“同情使用”的原则下,Regeneron提供了8克单剂量的REGN-COV2供特朗普总统使用。REGN-COV2是两种单克隆抗体的混合物(REGN10933和REGN10987),专门设计用于阻断SARS-CoV-2(引起COVID-19的病毒)的感染过程,是一种COVID-19研究性疗法。

该公司目前的首要任务是保持足够的REGN-COV2供应量,以便进行严格的临床试验,以全面评估其安全性和有效性。然而,经特殊情况批准的可用于“同情使用”的产品也很有限。“同情使用”的要求必须由主治医师提出。

目前正在评估REGN-COV2用于治疗和预防COVID-19的有效性和安全性。临床试验正在积极招募住院和非住院患者,以及COVID-19高感染风险的人群。本周早些时候,Regeneron宣布了早期数据,显示未经住院的COVID-19患者使用REGN-COV2治疗可降低病毒水平并改善症状。

 

原始出处:

https://www.firstwordpharma.com/node/1762552?tsid=4

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    2021-02-15 ms3000000788774334

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    2020-10-05 qblt
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    2020-10-03 14603802m96暂无昵称

    口服消毒液

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接受SACCOVID(CD24Fc)治疗的重症COVID-19患者恢复速度明显加快,并且疾病进展或呼吸衰竭的发生率显著降低。

J Endod:中国COVID-19爆发严重地区牙髓治疗的恢复情况:一项网络调查

这篇研究的目的是为了评估中国湖北省新冠疫情封闭结束后1个月牙髓治疗的恢复情况。

Novavax已在英国开始COVID-19候选疫苗NVX-CoV2373的III期临床试验

Novavax近日表示,已经启动了其第一项III期临床试验,以评估其COVID-19疫苗候选NVX-CoV2373的功效、安全性和免疫原性。

拓展阅读

Critical Care Medicine:气道压力释放通气模式在COVID-19导致急性呼吸 衰竭的患者中的应用:一项单中心随机对照试验

与小潮气量机械通气相比,APRV通气模式并未缩短重症新冠肺炎机械通气患者的机械通气时间,也未改善患者的其他临床结局。

Radiology:超极化氙气MRI显示长期COVID患者的肺部异常

胸部X线片(CXR)是诊断急性COVID-19肺炎最常用的成像方式,对于需要入院治疗的患者,通常会在急性感染三个月后重复检查。

Radiology:基于胸部CT的COVID-19肺炎后1年的预后评估

胸部CT对疾病监测至关重要,时间是充分评估肺部恢复能力的关键因素。

Am J Resp Crit Care:半乳糖凝集素-3抑制剂治疗COVID-19肺炎

在COVID-19肺炎中,吸入GB013治疗的耐受性良好,达到了临床相关的血浆浓度。该研究的数据支持更大规模的临床试验来明确GB013的临床疗效。

European Radiology:如何实现影像学的标准COVID-19全自动预测?

放射组学是一种利用数学算法量化医学成像中病变的表型特征的方法,可用于预测疾病的严重程度和进展。

Lenzilumab 治疗 COVID-19 住院患者,未达到主要终点

FDA 已经拒绝了该公司寻求紧急使用该疗法治疗新住院 COVID-19 患者的请求。美国监管机构确定,它无法得出 lenzilumab 的潜在益处超过潜在风险的结论。