Radiology:MR前交叉韧带黏液样变性与膝关节内侧骨性关节炎进展的相关性

2018-04-06 shaosai MedSci原创

本研究旨在验证发生或有骨性关节炎风险的患者出现前交叉韧带(ACL)黏液样变性与内侧胫股关节陷迫影像学进展风险的相关性,并将结果发表在Radiology上。

本研究旨在验证发生或有骨性关节炎风险的患者出现前交叉韧带(ACL)黏液样变性与内侧胫股关节陷迫影像学进展风险的相关性,并将结果发表在Radiology上。

本研究共纳入了600例骨性关节炎患者,并评价其基线时人口学特征、临床、影像学及磁共振骨性关节炎膝关节评分(MOAKS)数据。由两名骨肌专家采用盲法独立的评价基线时MR图像来识别ACL粘液变性。利用Logistic回归分析探究ACL粘液变性与ASL进展的相关性,JSL定义为关节间隙宽度减少超过0.7mm。基于基线软骨表面破坏程度进行分层分析。

结果为,合并ACL粘液变性的膝关节要较无ACL粘液变性的膝关节发生JSL进展的比例要高(64% vs 47%; P = .004)。在进行人口学特征、临床、影像及MOAKS变量校正后,ACL粘液变性与JSL并无统计学相关性(调整后OR为1.66; 95% CI: 1.00, 2.77; P = .051)。在亚组分析中,在无软骨破坏的受试者中ACL粘液变性与JSL进展具有显着相关性(软骨表面最大破坏比例 ≤75% [P = .015]和软骨表面破坏≤4个区域 [P = .028])。

本研究表明,在关节软骨表面无破坏的人群中,发生或有骨性关节炎风险的患者出现前交叉韧带(ACL)黏液样变性与内侧胫股关节陷迫影像学进展风险。

原始出处:


10.1148/radiol.2018171565

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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eeef1960262, createdName=杨柳青青, createdTime=Thu Apr 12 16:19:42 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=304873, encodeId=76c23048e320, content=签到学习了--, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eeef1960262, createdName=杨柳青青, createdTime=Wed Apr 11 21:41:05 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265671, encodeId=19c412656e11f, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, 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topicId=null, topicList=[TopicDto(id=32472, encryptionId=2a86324e2c9, topicName=前交叉韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9fd88269955, createdName=smartjoy, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507408, encodeId=f10e150e40822, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303327, encodeId=e5f130332ea5, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Apr 06 16:22:18 CST 2018, time=2018-04-06, status=1, ipAttribution=)]
    2018-04-12 杨柳青青

    签到学习了--

    0

  5. 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encryptionId=18ae103243a7, topicName=黏液样)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6ac207, createdName=xlwang2691, createdTime=Thu Feb 28 06:49:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837486, encodeId=899c183e48688, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sun Apr 22 02:49:00 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305118, encodeId=4856305118b5, content=签到学习了--, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, 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topicId=null, topicList=[TopicDto(id=32472, encryptionId=2a86324e2c9, topicName=前交叉韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9fd88269955, createdName=smartjoy, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507408, encodeId=f10e150e40822, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303327, encodeId=e5f130332ea5, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Apr 06 16:22:18 CST 2018, time=2018-04-06, status=1, ipAttribution=)]
    2018-04-11 杨柳青青

    签到学习了--

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1241305, encodeId=01e61241305a4, content=<a href='/topic/show?id=0c0d10166604' target=_blank style='color:#2F92EE;'>#骨性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101666, encryptionId=0c0d10166604, topicName=骨性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Sat Aug 27 01:20:39 CST 2022, time=2022-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822532, encodeId=d315182253240, content=<a href='/topic/show?id=18ae103243a7' target=_blank style='color:#2F92EE;'>#黏液样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103243, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eeef1960262, createdName=杨柳青青, createdTime=Thu Apr 12 16:19:42 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=304873, encodeId=76c23048e320, content=签到学习了--, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eeef1960262, createdName=杨柳青青, createdTime=Wed Apr 11 21:41:05 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265671, encodeId=19c412656e11f, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, 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topicId=null, topicList=[TopicDto(id=32472, encryptionId=2a86324e2c9, topicName=前交叉韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9fd88269955, createdName=smartjoy, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507408, encodeId=f10e150e40822, content=<a href='/topic/show?id=16b7100010c7' target=_blank style='color:#2F92EE;'>#韧带#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100010, encryptionId=16b7100010c7, topicName=韧带)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9b19890064, createdName=juliusluan81, createdTime=Sun Apr 08 05:49:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303327, encodeId=e5f130332ea5, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Apr 06 16:22:18 CST 2018, time=2018-04-06, status=1, ipAttribution=)]
    2018-04-08 lmm397
  7. 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    2018-04-08 huangdf
  8. 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  9. 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  10. 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    2018-04-06 清风拂面

    谢谢分享学习

    0

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世界各地和整个美国有数以百万计的人饱受骨关节炎的困扰。一项最新研究表明,富含膳食纤维的饮食可能会降低患膝关节炎的风险。

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研究的合著者,来自明尼苏达州罗切斯特梅奥诊所Robert和Arlene Kogod老年中心主任James Kirkland博士及其同事在《老年医学杂志,A辑:生物科学与医学科学》上发表了他们的研究结果。骨性关节炎(OA),又称为退行性关节疾病,是软骨组织——关节内保护骨骼末端的组织——不断磨损,导致其下方的骨骼产生摩擦所致的一种疾病。这种疾病可能会导致疼痛、肿胀、和关节运动障碍。当病情恶化时,骨骼

Ann Rheum Dis:口服氨基葡萄糖治疗膝关节和髋关节骨性关节炎有效吗?

2017年11月,发表在《Ann Rheum Dis》的一项系统评价和个体患者数据的Meta分析,调查了口服氨基葡萄糖治疗膝关节和髋关节骨性关节炎(OA)的有效性。

Arthritis Care Res:膝盖嘎吱作响,一定不要忽视!

在一项骨性关节炎的最新研究中,科学人员访问了3500名参与者,结果显示,膝盖如果发出摩擦声,嘎吱声或撕裂等声响的人们,是骨性关节炎的高风险人群。