Brit J Cancer:饮酒量、饮酒方式与癌症发生率

2020-10-13 MedSci原创 MedSci原创

饮酒会增加患癌症的风险,饮酒方式可能与患乳腺癌的风险独立相关。

尽管在国际上众所周知,饮酒会增加罹患多种癌症的风险,但有关饮酒方式与癌症风险的证据十分有限。

近日,肿瘤领域权威杂志British Journal of Cancer上发表了一篇研究文章,研究人员使用Cox比例风险回归对≥45岁(2006-2009年)的226162名参与者进行了分析,计算了与总酒精摄入量(饮/周)和饮酒方式有关的癌症风险校正后的风险比(HR)和95%置信区间(CI))。研究人员通过链接卫生记录联动中心与新南威尔士州癌症登记处确定了至2013年原发癌症病例。

在5.4年的中位随访期间,共诊断出17332例癌症病例。饮酒量增加与上呼吸道癌症(1.19; 1.10–1.29)、口和咽癌症(1.18; 1.08–1.29)、食道癌(1.22; 1.04–1.43)、结肠直肠癌(1.09; 1.04–1.15)、结肠癌(1.13; 1.06-1.20)、肝癌(1.22; 1.04–1.44)和乳腺癌(1.11; 1.02-1.21)的患病风险增加相关。喝酒方式与患乳腺癌的风险略有相关,而当摄入量集中在1-3天/周时,患乳腺癌的风险要高得多,相比于4-7天/周(相互作用P=0.049)。

由此可见,饮酒会增加患癌症的风险,饮酒方式可能与患乳腺癌的风险独立相关。

原始出处:

Peter Sarich.et al.Alcohol consumption, drinking patterns and cancer incidence in an Australian cohort of 226,162 participants aged 45 years and over.British Journal of Cancer.2020.https://www.nature.com/articles/s41416-020-01101-2

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    2021-04-10 huangdf
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    2020-10-18 内科

    看看

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1073754, encodeId=db3f10e375432, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=41265183741, createdName=14700eefm31暂无昵称, createdTime=Thu Nov 25 09:06:09 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826641, encodeId=fa1e182664181, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue May 04 12:43:56 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952982, encodeId=170b19529825a, content=<a href='/topic/show?id=6d061012155a' target=_blank style='color:#2F92EE;'>#饮酒量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101215, encryptionId=6d061012155a, topicName=饮酒量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sat Apr 10 02:43:56 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946118, encodeId=8fa6194611825, content=<a href='/topic/show?id=a244101210d5' target=_blank style='color:#2F92EE;'>#饮酒方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101210, encryptionId=a244101210d5, topicName=饮酒方式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Mon Feb 22 02:43:56 CST 2021, time=2021-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=892821, encodeId=9417892821ec, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200924/1f0d3a1b1b18443fa30de1daf0223787/f02372391ce2429baba98d30608a173e.jpg, createdBy=1b362235963, createdName=内科, createdTime=Sun Oct 18 11:46:19 CST 2020, time=2020-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891883, encodeId=f66f89188336, content=对于饮酒,滴酒不沾最好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Oct 13 22:11:27 CST 2020, time=2020-10-13, status=1, ipAttribution=)]
    2020-10-13 Jessica

    对于饮酒,滴酒不沾最好!

    0

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