JACC:有脂肪肝的房颤患者,消融后房颤复发风险高!

2020-08-15 xujing 中国循环杂志

学者在JACC临床电生理学子刊上发表研究称,合并脂肪肝的房颤患者消融后房颤复发风险升高。该研究中,56%的脂肪肝患者出现房颤复发,而没有脂肪肝的患者只有31%。

学者在JACC临床电生理学子刊上发表研究称,合并脂肪肝的房颤患者消融后房颤复发风险升高。

该研究中,56%的脂肪肝患者出现房颤复发,而没有脂肪肝的患者只有31%。

在多变量分析中,研究发现,脂肪肝使消融术后房颤复发风险增加2倍。

此外,研究还发现,肝纤维化程度越高,房颤复发率越高。与无纤维化或轻度纤维化的患者相比,中度肝纤维化患者的房颤复发率增加了近3倍(82% vs 31%)。

研究还发现,通过计算机断层扫描测量,合并脂肪肝患者的心外膜脂肪体积显着高于对照组(248 ml vs 223 ml)。

但进一步分析提示,心外膜脂肪量并不是房颤复发的重要预测因素。

研究者回顾性分析了267例房颤消融患者,其中89例术前确诊为脂肪肝,并根据年龄、性别、体重指数、射血分数和房颤类型与178例无脂肪肝患者进行配对。

所有患者在消融后至少随访12个月,并在肺静脉隔离术后3、6和12个月进行定期门诊,此后每年进行一次。平均随访29个月。

根据脂肪肝纤维化评分,89例脂肪肝患者中,13例为无或轻度肝纤维化,22例为严重肝纤维化,54例中度肝纤维化。

因此,研究者称,脂肪肝患者是房颤复发的高危人群。脂肪肝是一种可逆性疾病,应在消融前采用饮食和生活方式进行干以降低术后的复发风险。

原始出处:

Eoin Donnellan, Thomas G. Cotter, Oussama M. Wazni, et al.Impact of Nonalcoholic Fatty Liver Disease on Arrhythmia Recurrence Following Atrial Fibrillation Ablation.JACC.August 2020.DOI: 10.1016/j.jacep.2020.05.023.

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    2021-02-01 hbwxf
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    2020-08-15 心介

    房颤,临床上碰到很多哦

    0

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