Hypertension:家用细颗粒物空气过滤器对血压的影响

2020-06-02 MedSci原创 MedSci原创

鉴于研究设计的差异,有必要进行额外的研究以确认和更好地量化使用个人空气过滤器对收缩压的益处。

空气污染是导致心血管疾病发病率和死亡率的主要因素。直径<2.5 µm的细颗粒物可能是高血压可改变的危险因素。目前尚不清楚家庭空气过滤对收缩压和舒张压的益处。近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员旨在评估使用家用个人空气净化器对细颗粒物暴露和血压的影响。

研究人员在PubMed、Web of Science、Cochrane Central Register、Inspec和EBSCO GreenFILE数据库中对相关临床试验进行了检索。纳入的研究仅限于无烟房屋中的非吸烟参与者,这些房屋对室内细颗粒物浓度进行了主动过滤或假过滤,并记录了参与者的收缩压和舒张压变化。

在确定的330篇文献中,10项试验共招募了604名符合纳入标准的参与者。在中位数为13.5天的随访期间,平均收缩压显著降低了≈4mm Hg(-3.94 mmHg [95%CI为-7.00至-0.89];P=0.01),但平均舒张压无显著差异(-0.95 mmHg [95%CI为-2.81至0.91]; P=0.32)。亚组分析表明,按年龄、细颗粒物浓暴露水平或研究持续时间,效应没有异质性。

鉴于研究设计的差异,有必要进行额外的研究以确认和更好地量化使用个人空气过滤器对收缩压的益处。

原始出处:

Dalia Walzer.et al.Effects of Home Particulate Air Filtration on Blood Pressure A Systematic Review.Hypertension.2020.https://www.ahajournals.org/toc/hyp/0/0

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    2020-09-15 lisa449
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    2021-01-23 feather89
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