Gastroenterology:基线结肠镜结果与长期晚期肿瘤风险

2019-08-06 MedSci MedSci原创

研究认为,基线筛查结肠镜检查结果与10年内的晚期肿瘤风险有关。在基线只有1或2个小腺瘤的个体在10年内患上晚期肿瘤的风险很低

很少有研究考察筛查人群进行结肠镜筛查和监测的长期结果。近日研究人员就筛查人群的晚期肿瘤的10年风险(定义为腺瘤≥10毫米,腺瘤有绒毛组织学或高度发育不良,或直肠癌[CRC])进行了考察,并评估基线结肠镜检查结果与长期预后的相关性。

3121名无症状退伍军人(50-75岁)参与研究,这些退伍军人从1994年到1997年在13个医疗中心接受了结肠镜检查,随后随访10年或直至死亡。

经过10年的随访,在所有基线结肠镜检查组中,146名患者发现至少1例晚期肿瘤。晚期肿瘤的累积10年发病率在基线CRC患者中最高(43.7%),其次是基线AA人群(21.9%)。基线1-2腺瘤和非腺瘤的10年累积发病率分别为6.3%和4.1%。调整后,与无基线肿瘤的退伍军人相比,基线时有1或2个小腺瘤的退伍军人在每次监测检查时发生晚期肿瘤的风险没有显著增加(OR:0.96)。

研究认为,基线筛查结肠镜检查结果与10年内的晚期肿瘤风险有关。在基线只有1或2个小腺瘤的个体在10年内患上晚期肿瘤的风险很低。

原始出处:


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    2019-12-30 许安
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    2019-08-08 zhouqu_8
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  8. [GetPortalCommentsPageByObjectIdResponse(id=2064802, encodeId=cd362064802fb, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sat Oct 26 10:21:00 CST 2019, time=2019-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2072667, encodeId=f46820e2667e1, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Mon Dec 30 09:21:00 CST 2019, time=2019-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712056, encodeId=310b1e1205606, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Jan 07 19:21:00 CST 2020, time=2020-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2026042, encodeId=b978202604256, content=<a href='/topic/show?id=c3048314322' target=_blank style='color:#2F92EE;'>#肿瘤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83143, encryptionId=c3048314322, topicName=肿瘤风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Wed Feb 05 17:21:00 CST 2020, time=2020-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1709470, encodeId=e8a41e0947038, content=<a href='/topic/show?id=cf4a598e795' target=_blank style='color:#2F92EE;'>#晚期肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59877, encryptionId=cf4a598e795, topicName=晚期肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=926b31711313, createdName=ms705947299214030, createdTime=Mon Jan 06 16:21:00 CST 2020, time=2020-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434492, encodeId=e58f1434492a9, content=<a href='/topic/show?id=95de81e4889' target=_blank style='color:#2F92EE;'>#肠镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81748, encryptionId=95de81e4889, topicName=肠镜)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 08 10:21:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504754, encodeId=2c851504e547a, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Thu Aug 08 10:21:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370873, encodeId=07753e087363, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Tue Aug 06 19:27:23 CST 2019, time=2019-08-06, status=1, ipAttribution=)]
    2019-08-06 一个字-牛

    学习了谢谢分享

    0

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