J Periodontol:引导性组织再生结合同种异体骨移植治疗骨缺损

2020-06-27 网络 网络

目前,引导组织再生(GTR)的结果的临床数据很少。这项回顾性队列研究的目的是评估GTR后的预后,稳定性以及治疗后牙齿的存活率。

目前,引导组织再生(GTR)的结果的临床数据很少。这项回顾性队列研究的目的是评估GTR后的预后,稳定性以及治疗后牙齿的存活率。

研究包括使用生物可吸收膜和骨移植替代物的GTR治疗的骨缺损以及为期1年以上的随访期。进行生存和回归分析评估预后,其稳定性和牙齿的固位。通过Cox比例风险模型和多元广义线性模型评估记录的变量对临床附着量(CAL)和牙齿存活的影响。

选择175个治疗后的骨缺损,平均随访时间为5.75±4.6年。在基线时,平均CAL为9.56±1.93 mm,平均牙周袋深度(PD)为8.41±1.42 mm。术后1年复诊时,CAL增加3.55±1.85 mm,PD减少3.87±1.87 mm(P <0.05)。经治疗的牙齿的5年和10年存活率分别为85.0%和72.7%。基线PD,吸烟和膜暴露与CAL增加显著相关,而基线CAL,年龄,维持就诊次数显著影响牙齿的存活。

在这项研究的局限性内,GTR可以提高牙齿存活率和整体临床效果,是治疗骨缺损的不错的选择。

原文出处:

Jad Majzoub,Guided tissue regeneration combined with bone allograft in infrabony defects: Clinical outcomes and assessment of prognostic factors. Journal of periodontology, 2020 June. Doi: 10.1002/JPER.19-0336

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    2020-11-23 howi
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    2021-06-06 feather89
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    2020-06-29 lfcmxl
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