Heart:急性心力衰竭患者冠状动脉旁路移植术与经皮冠状动脉介入治疗比较

2018-09-13 xing.T MedSci原创

由此可见,与PCI相比,CABG与AHF患者的全因死亡率显著降低有关。进一步的研究应评估AHF患者适当的血运重建策略。

心肌缺血是急性心力衰竭(AHF)的主要原因。然而,AHF的最佳血运重建策略尚不清楚。近日,心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员旨在比较AHF患者的两种血运重建策略的疗效,冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)。

从2011年3月至2014年2月期间,在韩国急性心力衰竭登记中心前瞻性登记的5625例患者中,717例在AHF住院期间接受CABG或PCI的患者被纳入本分析。研究人员使用倾向评分匹配比较了不良结局(死亡、HF加重或血管原因的再入院、缺血性卒中以及HF加重或血管原因的死亡和再住院的复合结局)。

对于包含190名患者的倾向评分匹配队列,中位随访4年,CABG的全因死亡风险低于PCI(83例 vs. 147例死亡每1000例患者每年; HR为0.57,95%CI为0.34-0.96,p=0.033)。由于心血管事件或HF加重,还存在降低再入院率的趋势。亚组分析显示,CABG组的不良结局显著低于PCI组,特别是老年、三支血管疾病、显著的左前降支近端动脉疾病和无左主干血管疾病或慢性完全闭塞的患者。

由此可见,与PCI相比,CABG与AHF患者的全因死亡率显著降低有关。进一步的研究应评估AHF患者适当的血运重建策略。

原始出处:

Sang Eun Lee.et al. Coronary artery bypass graft versus percutaneous coronary intervention in acute heart failure.Heart. 2018. http://dx.doi.org/10.1136/heartjnl-2018-313242

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    2018-11-23 cy0324
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  5. 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  6. 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15 00:25:00 CST 2018, time=2018-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344838, encodeId=ef7334483855, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Sep 13 13:31:35 CST 2018, time=2018-09-13, status=1, ipAttribution=)]
    2018-09-15 zhaojie88
  8. 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15 00:25:00 CST 2018, time=2018-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344838, encodeId=ef7334483855, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Sep 13 13:31:35 CST 2018, time=2018-09-13, status=1, ipAttribution=)]
    2018-09-15 slcumt
  9. 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    2018-09-13 医者仁心5538

    学习了

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