BMJ Evidence-based Medicine:神奇!牛津大学证明:治疗感冒、咳嗽,蜂蜜比抗生素管用

2020-08-26 生物探索 生物探索

蜂蜜治疗上呼吸道感染更有效

上呼吸道感染(URTIs),狭义上被称为感冒,是一种由致病微生物侵入呼吸道并进行繁殖导致的疾病。临床上往往使用抗生素(主要针对细菌)进行治疗,但由于大多数URTI是病毒性的,抗生素治疗不仅效果不佳,还可能会因过度使用而造成细菌的抗生素耐药性。

最近,《BMJ Evidence-based Medicine》发布的一篇文章提出,蜂蜜——这种日常生活中常见的营养品,或许是一种更为理想的URTIs治疗方式。在这篇文章中,牛津大学的研究人员通过对14篇与URTIs及蜂蜜有关的文献进行系统分析,发现蜂蜜在改善患者综合症状、咳嗽频率和咳嗽严重程度方面的效果显着优于目前的常规护理方法。

http://dx.doi.org/10.1136/bmjebm-2020-111336

作为一种常见的民间疗法,蜂蜜用于治疗感冒、咳嗽的传统已经沿袭了数千年。这种由蜜蜂酿造的蜂糖,70%的成分是果糖和葡萄糖,此外还含有人体必需的氨基酸、蛋白质、维生素、活性酶及微量元素等多种营养物质。

为了评估蜂蜜在治疗URTIs方面的有效性,研究人员首先通过关键词和MeSH词表搜索到1345项与URTIs有关的文献,在排除了关联性不大以及质量不高的文献后,最终筛选出14份临床试验报告,涵盖1761名患者。

使用RevMan 5.3软件对这些数据进行分析时,研究人员发现,这些试验基本上囊括了所有治疗URTIs的传统疗法,其中11份报告涉及纯蜂蜜以及蜂蜜与药物、咖啡、牛奶等物质结合的疗法(统称“蜂蜜疗法”),3项报告涉及常见的含蜂蜜成分的止咳糖浆。

14项纳入分析的研究的特征

除咳嗽症状外,这项研究的评估标准还包括睡眠困难、总体主观症状和鼻炎、肌痛、充血和咳嗽的持续时间。

在对所有数据进行整合后,研究人员发现,蜂蜜疗法能够有效改善URTI患者的综合症状、咳嗽频率以及咳嗽时间。具体而言,蜂蜜疗法让患者的咳嗽频率降低了36%,咳嗽的严重程度降低了44%,同时患者感染的持续时间平均缩短了两天。

与常规治疗相比时,接受蜂蜜疗法的患者在综合症状评分、咳嗽频率和咳嗽严重程度方面的变化

为什么蜂蜜具有如此神奇的疗效?关于这个问题,或许能够从2014年美国化学学会(ACS)第247届全国会议上的一份报告中窥见答案。

在这份报告中,萨乌瑞吉纳大学的Susan M. Meschwitz提出,蜂蜜可能是解决严重且日益增长的细菌对抗生素耐药性问题的一种“甜蜜”方法。

这主要是由于蜂蜜中含有多种细菌“大杀器”,比如,高效抗菌物质过氧化氢,这是蜂蜜有极强抗菌能力的主要原因,高糖浓度带来的渗透效应能够让细菌细胞脱水,另外抗氧化剂多酚也具有一定的灭菌效果。不仅仅是抗细菌,大量的研究已经证明,蜂蜜还具有抗真菌和抗病毒的特性。

尽管这项研究存在着一些缺陷,比如纳入分析的研究中可能存在偏倚风险、难以评估混合疗法中蜂蜜的作用,但这是目前评估蜂蜜改善一系列上呼吸道感染症状的最全面的系统分析,表明与抗生素相比,蜂蜜或许是一种更便宜、可得且危害更小的治疗方法。当然,仍然需要进行更高质量及更大规模的安慰剂对照试验以评估蜂蜜在治疗上呼吸道感染方面的效果。

原始出处:

Hibatullah Abuelgasim, et al. Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis. BMJ Evidence-based Medicine,2020.

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    2021-09-15 ms2000001585534514

    学习了,觉得很有帮助,之后可以试试

    0

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    2020-11-09 jeanqiuqiu
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    2021-05-08 1253e9e9m58暂无昵称

    学习了

    0

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    2021-02-21 kalseyzl
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    2021-02-23 珠珠

    学习了,很好

    0

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    2021-01-12 珠珠

    受教了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1051384, encodeId=c6091051384db, content=学习了,觉得很有帮助,之后可以试试, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5da5557703, createdName=ms2000001585534514, createdTime=Wed Sep 15 08:57:33 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1859066, encodeId=3bba18590664a, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Mon Nov 09 17:04:32 CST 2020, time=2020-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=963630, encodeId=0737963630a7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d67d2550313, createdName=1253e9e9m58暂无昵称, createdTime=Sat May 08 09:31:13 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773874, encodeId=94681e7387477, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Feb 21 05:04:32 CST 2021, time=2021-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=926556, encodeId=8cbf926556db, content=学习了,很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Feb 23 10:38:39 CST 2021, time=2021-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915980, encodeId=986b915980d6, content=受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Jan 12 18:25:35 CST 2021, time=2021-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849086, encodeId=4e911849086ff, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Mar 20 07:04:32 CST 2021, time=2021-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=887884, encodeId=a6a988e8847e, content=新知识点, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200918/d90a11116fc1402eb5f7f8d1ccf476fa/5b9b94932b2c4426beb28e90ebb0c2f6.jpg, createdBy=1c142622023, createdName=小萌新der, createdTime=Thu Sep 24 10:41:23 CST 2020, time=2020-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885103, encodeId=c62c8851039b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d4d2326628, createdName=1225f870m98(暂无昵称), createdTime=Mon Sep 14 09:54:38 CST 2020, time=2020-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882646, encodeId=972788264616, content=学习了,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Fri Sep 04 09:22:35 CST 2020, time=2020-09-04, status=1, ipAttribution=)]
    2021-03-20 gaoxiaoe
  8. [GetPortalCommentsPageByObjectIdResponse(id=1051384, encodeId=c6091051384db, content=学习了,觉得很有帮助,之后可以试试, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5da5557703, createdName=ms2000001585534514, createdTime=Wed Sep 15 08:57:33 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1859066, encodeId=3bba18590664a, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Mon Nov 09 17:04:32 CST 2020, time=2020-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=963630, encodeId=0737963630a7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d67d2550313, createdName=1253e9e9m58暂无昵称, createdTime=Sat May 08 09:31:13 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773874, encodeId=94681e7387477, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Feb 21 05:04:32 CST 2021, time=2021-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=926556, encodeId=8cbf926556db, content=学习了,很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Feb 23 10:38:39 CST 2021, time=2021-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915980, encodeId=986b915980d6, content=受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Jan 12 18:25:35 CST 2021, time=2021-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849086, encodeId=4e911849086ff, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Mar 20 07:04:32 CST 2021, time=2021-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=887884, encodeId=a6a988e8847e, content=新知识点, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200918/d90a11116fc1402eb5f7f8d1ccf476fa/5b9b94932b2c4426beb28e90ebb0c2f6.jpg, createdBy=1c142622023, createdName=小萌新der, createdTime=Thu Sep 24 10:41:23 CST 2020, time=2020-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885103, encodeId=c62c8851039b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d4d2326628, createdName=1225f870m98(暂无昵称), createdTime=Mon Sep 14 09:54:38 CST 2020, time=2020-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882646, encodeId=972788264616, content=学习了,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Fri Sep 04 09:22:35 CST 2020, time=2020-09-04, status=1, ipAttribution=)]
    2020-09-24 小萌新der

    新知识点

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1051384, encodeId=c6091051384db, content=学习了,觉得很有帮助,之后可以试试, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5da5557703, createdName=ms2000001585534514, createdTime=Wed Sep 15 08:57:33 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1859066, encodeId=3bba18590664a, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Mon Nov 09 17:04:32 CST 2020, time=2020-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=963630, encodeId=0737963630a7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d67d2550313, createdName=1253e9e9m58暂无昵称, createdTime=Sat May 08 09:31:13 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773874, encodeId=94681e7387477, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Feb 21 05:04:32 CST 2021, time=2021-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=926556, encodeId=8cbf926556db, content=学习了,很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Feb 23 10:38:39 CST 2021, time=2021-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915980, encodeId=986b915980d6, content=受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Jan 12 18:25:35 CST 2021, time=2021-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849086, encodeId=4e911849086ff, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Mar 20 07:04:32 CST 2021, time=2021-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=887884, encodeId=a6a988e8847e, content=新知识点, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200918/d90a11116fc1402eb5f7f8d1ccf476fa/5b9b94932b2c4426beb28e90ebb0c2f6.jpg, createdBy=1c142622023, createdName=小萌新der, createdTime=Thu Sep 24 10:41:23 CST 2020, time=2020-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885103, encodeId=c62c8851039b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d4d2326628, createdName=1225f870m98(暂无昵称), createdTime=Mon Sep 14 09:54:38 CST 2020, time=2020-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882646, encodeId=972788264616, content=学习了,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Fri Sep 04 09:22:35 CST 2020, time=2020-09-04, status=1, ipAttribution=)]
    2020-09-14 1225f870m98(暂无昵称)

    学习

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1051384, encodeId=c6091051384db, content=学习了,觉得很有帮助,之后可以试试, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5da5557703, createdName=ms2000001585534514, createdTime=Wed Sep 15 08:57:33 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1859066, encodeId=3bba18590664a, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Mon Nov 09 17:04:32 CST 2020, time=2020-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=963630, encodeId=0737963630a7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d67d2550313, createdName=1253e9e9m58暂无昵称, createdTime=Sat May 08 09:31:13 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773874, encodeId=94681e7387477, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sun Feb 21 05:04:32 CST 2021, time=2021-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=926556, encodeId=8cbf926556db, content=学习了,很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Feb 23 10:38:39 CST 2021, time=2021-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=915980, encodeId=986b915980d6, content=受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Tue Jan 12 18:25:35 CST 2021, time=2021-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849086, encodeId=4e911849086ff, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Mar 20 07:04:32 CST 2021, time=2021-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=887884, encodeId=a6a988e8847e, content=新知识点, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200918/d90a11116fc1402eb5f7f8d1ccf476fa/5b9b94932b2c4426beb28e90ebb0c2f6.jpg, createdBy=1c142622023, createdName=小萌新der, createdTime=Thu Sep 24 10:41:23 CST 2020, time=2020-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885103, encodeId=c62c8851039b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d4d2326628, createdName=1225f870m98(暂无昵称), createdTime=Mon Sep 14 09:54:38 CST 2020, time=2020-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=882646, encodeId=972788264616, content=学习了,挺好, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa7b5413394, createdName=珠珠, createdTime=Fri Sep 04 09:22:35 CST 2020, time=2020-09-04, status=1, ipAttribution=)]
    2020-09-04 珠珠

    学习了,挺好

    0

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