Gastroenterology:全球胰腺癌发病率和死亡率趋势研究

2020-10-20 MedSci原创 MedSci原创

通过对184个国家的数据进行分析后,研究发现全球范围内胰腺癌的发病率和死亡率呈上升趋势,尤其是在女性女和50岁以上的人群中

近日研究人员评估了不同性别和年龄组胰腺癌的全球和区域负担、危险因素和流行病学趋势。
 
研究人员使用GLOBOCAN数据库数据来估计184个国家的胰腺癌发病率和死亡率。研究了生活方式和代谢危险因素之间的关系,通过单变量和多变量线性回归分析考察了胰腺癌发病率和死亡率。从48个国家的癌症登记处检索了截至2017年的特定国家的年龄标准化(ASRs)发病率和死亡率。
 
2018年,在极高(ASRs,7.7和4.9)及较高(ASRs,6.9和4.6)人类发展指数(HDIs,可反映发达程度)国家,胰腺癌发病率和死亡率是最高的。发病率和死亡率较高国家的吸烟、饮酒、缺乏运动、肥胖、高血压和高胆固醇患病率较高。根据统计数据,分别有14个国家(平均年变化百分比[AAPCs]为8.85至0.41)和17个国家(AAPCs,6.04至0.87)的男性和女性胰腺癌发病率有所上升。在死亡率方面,有8个国家(AAPCs,4.20至0.55)的男性和14个国家(AAPCs,5.83至0.78)的女性患者的死亡率上升。在18个国家(AAPCs,7.83-0.91)中,50岁或50岁以上的人群的胰腺癌发病率有所上升,但在8个国家(AAPCs,8.75-2.82)和4个国家(AAPCs,11.07-8.31)中,50岁以下和40岁以下的胰腺癌发病率也呈上升趋势。
 
通过对184个国家的数据进行分析后,研究发现全球范围内胰腺癌的发病率和死亡率呈上升趋势,尤其是在女性和50岁以上的人群中。
 
原始出处:
 
Junjie Huang et al. Worldwide Burden of, Risk Factors for, and Trends in Pancreatic Cancer.Gastroenterology. October 12,2020.

 

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1712589, encodeId=4ee01e1258986, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue May 11 21:09:31 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2065190, encodeId=0eb22065190bc, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Nov 27 22:09:31 CST 2020, time=2020-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1799885, encodeId=35fa1e998852e, content=<a href='/topic/show?id=9e3fe127909' target=_blank style='color:#2F92EE;'>#癌发病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71279, encryptionId=9e3fe127909, topicName=癌发病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2c92500045, createdName=12498636m49(暂无昵称), createdTime=Wed Jan 20 21:09:31 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073148, encodeId=04b720e3148bf, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Mon Jul 19 18:09:31 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2079285, encodeId=ca9c20e92855e, content=<a href='/topic/show?id=659ce1280ee' target=_blank style='color:#2F92EE;'>#癌发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71280, encryptionId=659ce1280ee, topicName=癌发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1777154, createdName=chenhongpeng, createdTime=Thu Apr 15 19:09:31 CST 2021, time=2021-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823676, encodeId=5bd218236e6e4, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Tue Apr 20 10:09:31 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505119, encodeId=2c7d1505119ba, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Thu Oct 22 10:09:31 CST 2020, time=2020-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893497, encodeId=39c189349eae, content=全球范围内胰腺癌的发病率和死亡率呈上升趋势,尤其是在女性和50岁以上的人群中,发病率和死亡率较高国家的吸烟、饮酒、缺乏运动、肥胖、高血压和高胆固醇患病率较高。不吸烟,不喝酒,适量运动、健康饮食保平安。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Oct 21 11:13:51 CST 2020, time=2020-10-21, status=1, ipAttribution=)]
    2021-07-19 许安
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    2020-10-21 Jessica

    全球范围内胰腺癌的发病率和死亡率呈上升趋势,尤其是在女性和50岁以上的人群中,发病率和死亡率较高国家的吸烟、饮酒、缺乏运动、肥胖、高血压和高胆固醇患病率较高。不吸烟,不喝酒,适量运动、健康饮食保平安。

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TAG:二甲双胍在胰腺神经内分泌肿瘤患者治疗中的潜在作用

胰腺神经内分泌肿瘤(panNETs)是一组具有异质生物学特征和临床行为的恶性肿瘤,其发病率在全世界范围内均有增加。