Aliment Pharmacol Ther:类固醇可有效治疗食管扁平苔癣

2016-11-21 MedSci MedSci原创

食管扁平苔癣是一种特发性炎症性疾病,具有显着的食管狭窄特征。食管扁平苔癣是一个罕见且很难诊断的疾病。目前没有标准化的治疗方法,治疗策略也各不相同。 研究目的是调查类固醇治疗(氟替卡松和布地奈德)对食管扁平苔藓的疗效。 对1995和2016之间在罗切斯特梅奥诊所诊断为食管扁平苔癣的患者进行了回顾性研究。上消化道内镜检查的平均时间为3.2个月(0.7 - 11.7)。吞食类固醇制剂包括氟替

食管扁平苔癣是一种特发性炎症性疾病,具有显着的食管狭窄特征。食管扁平苔癣是一个罕见且很难诊断的疾病。目前没有标准化的治疗方法,治疗策略也各不相同。

研究目的是调查类固醇治疗(氟替卡松和布地奈德)对食管扁平苔藓的疗效。

对1995和2016之间在罗切斯特梅奥诊所诊断为食管扁平苔癣的患者进行了回顾性研究。上消化道内镜检查的平均时间为3.2个月(0.7 - 11.7)。吞食类固醇制剂包括氟替卡松880μg每日两次或布地奈德3 mg每日2次。采用Dakkak-Bennett吞咽困难得分评估患者的治疗反应(0–4,无吞咽困难到不能摄食)。

我们确定了40例符合纳入标准的患者,类固醇治疗后吞咽困难评分从1降低到0(P < 0.001)。62%的患者反应类固醇治疗后吞咽困难问题得以结局,72.5%的患者对类固醇治疗有内镜下的反应。

布地奈德或氟替卡松治疗食管扁平苔癣是有效的。

原始出处:

A. Podboy, D. Sunjaya, T. C. Smyrk, J. A. Murray, M. Binder, D. A. Katzka, J. A. Alexander and M. Halland.Oesophageal lichen planus: the efficacy of topical steroid-based therapies.Aliment Pharmacol Ther.17 NOV 2016

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    2016-12-27 yb6560
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    2017-03-24 jj000001
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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 22 14:28:21 CST 2016, time=2016-11-22, status=1, ipAttribution=)]
    2016-11-25 虈亣靌

    讲的好,学习了

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 22 14:28:21 CST 2016, time=2016-11-22, status=1, ipAttribution=)]
    2016-11-23 zhouqu_8
  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 22 14:28:21 CST 2016, time=2016-11-22, status=1, ipAttribution=)]
    2016-11-22 ylzr123

    食管扁平苔癣是一种特发性炎症性疾病,具有显着的食管狭窄特征。食管扁平苔癣是一个罕见且很难诊断的疾病。目布地奈德或氟替卡松治疗食管扁平苔癣是有效的。

    0

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