Sci Rep:手术切除的食管鳞状细胞癌

2020-03-29 xiangting MedSci原创

对于可手术切除的eSCC患者,在PET/CT时测量原发肿瘤的SUVmax可以帮助预测患者的生存率。

这项研究旨在报告eSCC手术切除后的患者生存情况,并确定与患者预后相关的临床、影像和病理学因素。

这一回顾性研究纳入435例eSCC≤T2期患者(中位随访时间,49.3个月)。共有103例患者死亡(23.7%),89例患者(20.5%)在随访期间复发。原发肿瘤正电子发射计算机断层扫描(PET)/计算机断层扫描(CT)上的最大标准化摄取值(SUVmax)与肿瘤长度、淋巴结转移和病理性T分期呈正线性相关。在多因素分析中,PET/CT的SUVmax较高是无病生存期(DFS)和总生存期(OS)的不良预后因素。相反,淋巴结转移只是DFS的预后因素,而病理T分期只是OS的预后因素。通过应用SUVmax阈值,按阈值分组(A:SUVmax≤3.05,B:SUVmax 3.06-5.64,C:SUVmax≥5.65),三组的DFS和OS均明显不同。

对于可手术切除的eSCC患者,在PET/CT时测量原发肿瘤的SUVmax可以帮助预测患者的生存率。此外,PET/CT提供了内镜粘膜下剥离的病人分类标准(ESD; T1a癌和SUVmax,≤3.05)。

原始出处:

Dong Young Jeong. Surgically Resected Esophageal Squamous Cell Carcinoma: Patient Survival and Clinicopathological Prognostic Factors. Sci Rep. 19 March 2020.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1978960, encodeId=e9d319e8960fd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Fri May 08 01:14:08 CST 2020, time=2020-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378868, encodeId=268913e886813, content=<a href='/topic/show?id=b860101129ac' target=_blank style='color:#2F92EE;'>#食管鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429438, encodeId=bf481429438be, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437526, encodeId=cfc3143e52649, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1978960, encodeId=e9d319e8960fd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Fri May 08 01:14:08 CST 2020, time=2020-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378868, encodeId=268913e886813, content=<a href='/topic/show?id=b860101129ac' target=_blank style='color:#2F92EE;'>#食管鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429438, encodeId=bf481429438be, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437526, encodeId=cfc3143e52649, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1978960, encodeId=e9d319e8960fd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Fri May 08 01:14:08 CST 2020, time=2020-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378868, encodeId=268913e886813, content=<a href='/topic/show?id=b860101129ac' target=_blank style='color:#2F92EE;'>#食管鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429438, encodeId=bf481429438be, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437526, encodeId=cfc3143e52649, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1978960, encodeId=e9d319e8960fd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Fri May 08 01:14:08 CST 2020, time=2020-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378868, encodeId=268913e886813, content=<a href='/topic/show?id=b860101129ac' target=_blank style='color:#2F92EE;'>#食管鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429438, encodeId=bf481429438be, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437526, encodeId=cfc3143e52649, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Mar 31 07:14:08 CST 2020, time=2020-03-31, status=1, ipAttribution=)]
    2020-03-31 zhouqu_8

相关资讯

2020 专家共识:FDG PET/CT在感染和炎症中的应用

为了进一步促进 18F-FDG PET-CT在感染和炎症中的临床应用,规范诊断流程,中国有关领域内的专家对上述内容进行讨论,形成了专家共识。

Gastric Cancer :内脏脂肪组织CT衰减和F-18氟脱氧葡萄糖摄取对预测根治性手术切除后胃癌患者生存的意义

背景及目的:本项研究的目的是探究计算机断层扫描(CT)衰减和内脏脂肪组织(VAT)摄取F-18氟脱氧葡萄糖(FDG)的预后意义,以预测腹膜无复发生存期(RFS)以及RFS和总体晚期胃癌(AGC)患者的

Lancet:前列腺特异性膜抗原PET-CT用于高危前列腺癌患者分期

PSMA PET-CT可替代常规CT和骨扫描用于高危前列腺癌患者分期

Stroke:用PET评估颈动脉狭窄患者复发性脑卒中的风险!

在症状性颈动脉内膜剥脱术随机试验中,仅有中度狭窄的患者可能从中获益,有些重度狭窄的患者从中并无法获益。颈动脉斑块18F-氟脱氧葡萄糖PET能够反映斑块炎症反应,能够预测复发性脑卒中。

Radiology:霍奇金淋巴瘤和侵入性非霍奇金淋巴瘤分期和治疗方案制定借助CT好还是PET/CT好?

本研究旨在验证局限性(LS)霍奇金淋巴瘤(HL)或侵入性非-HL(ANHL)临床治疗、预后与PET/CT分期的相关性。

国产临床全数字PET/CT获准进入市场

华中科技大学谢庆国教授团队发明的全数字PET/CT,日前已通过国家药品监督管理局注册审批,获得市场准入和对外销售资质。这意味着国产全数字PET打破国际技术垄断,我国高端医疗仪器开发取得重大突破。PET是正电子发射断层成像的简称,是一种生化灵敏度极高的核医学分子影像技术,PET/CT将CT与PET融为一体,由CT提供解剖位置信息的同时,PET提供功能等分子信息,从而助力恶性肿瘤等病灶的早期发现和精准