BMJ:家庭中水痘患儿可降低成年人带状疱疹风险

2020-01-28 MedSci MedSci原创

研究发现,家庭中存在儿童水痘患儿可降低成人的带状疱疹风险,这一风险降低效果适中且可以长期保持

近日研究人员考察了水痘患儿对成年人群带状疱疹风险的影响。

本次研究的参与者为9604名成年带状疱疹患者,患者于1997-2018年间确诊。在观察期中,患者家中存在1名18岁以下儿童亲属被诊断患有水痘。研究的主要终点为随后20年内家庭成员的带状疱疹风险。

9604名成年带状疱疹患者中,女性占68.6%,平均观察期为14.7年。相对于所有时间段,水痘暴露期带状疱疹风险降低:所有时间段带状疱疹发病4116例、水痘暴露期内发病433例。多因素调整后,家庭内水痘儿童降低了33%的成年人带状疱疹风险。在水痘暴露后10-20年,成人的带状疱疹风险降低27%。男性暴露后风险降低效果优于女性。

研究发现,家庭中存在儿童水痘患儿可降低成人的带状疱疹风险,这一风险降低效果适中且可以长期保持。

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    2020-03-16 gaoxiaoe
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    2020-01-30 1478fa69m73暂无昵称

    学习了

    0

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