Nutrients:饮食中黄酮类化合物的摄入量与10年的年龄相关的听力损失发生率之间的关系

2020-11-02 AlexYang MedSci原创

饮食中的黄酮类化合物是具有抗炎特性的血管活性植物化学物质。最近,有研究人员评估了6种常见的黄酮类物质的基线摄入量与10年年龄相关听力损失发生率之间的关联。

饮食中的黄酮类化合物是具有抗炎特性的血管活性植物化学物质。最近,有研究人员评估了6种常见的黄酮类物质的基线摄入量与10年年龄相关听力损失发生率之间的关联。

研究种,共有1691名50岁以上的参与者有饮食摄入量和听力状况的信息。听力损失定义为在频率0.5、1.0、2.0和4.0 kHz时的纯音平均值>25 dB听力水平(HL)。饮食数据通过半定量的食物频率问卷收集,并利用美国数据库估算食物中黄酮类化合物的含量。研究发现,在10年的随访中,260名参与者(31.6%)发生了新的听力损失(事件)。多变量调整后,饮食异黄酮摄入量第四与第一四分位数(参考组)的参与者相比,在10年后发生听力损失发生的风险降低了36%:OR为0.64(95%CI,0.42-0.99);趋势的P值为0.03。研究人员在其他5个黄酮类亚类和10年听力损失发生率之间没有观察到显著的关联。

基线类黄酮摄入量与10年双侧年龄相关性听力损失发生率之间的多变量调整后相关性

最后,研究人员指出,他们的研究结果并不支持饮食中黄酮类化合物的摄入可以保护听力损失长期风险的假设。研究人员也指出,与异黄酮摄入量的关联性还需要其他基于人群的研究来证实。

原始出处:

Bamini Gopinath , Catherine M McMahon , Joshua R Lewis et al. Associations between Intake of Dietary Flavonoids and 10-Year Incidence of Age-Related Hearing Loss. Nutrients. Oct 2020

 

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    2021-10-20 ms4000000508774213

    听力损失与类黄酮异黄酮

    0

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    2021-09-06 lmm397
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    2021-01-05 fengyi821
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    2020-11-04 ysjykql
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    2020-11-02 Jessica

    研究结果并不支持饮食中黄酮类化合物的摄入可以保护听力损失长期风险的假设

    0

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