尿白蛋白排泄率是老年2型糖尿病并发冠心病主要危险因素

2012-08-10 立影 摘编 医学论坛网

  近日,卫生部北京医院内分泌科的郭立新、马靖、程洋等人共同发表论文,旨在应用主成分分析法(principal component analysis,PCA)分析老年2型糖尿病患者并发冠心病的主要危险因素。研究指出,尿白蛋白排泄率(UAER)是老年2型糖尿病患者并发冠心病最主要的危险因素,伴微量白蛋白尿的老年2型糖尿病患者冠心病患病风险增加,且严重程度增加;UAER与老年2型糖

  近日,卫生部北京医院内分泌科的郭立新、马靖、程洋等人共同发表论文,旨在应用主成分分析法(principal component analysis,PCA)分析老年2型糖尿病患者并发冠心病的主要危险因素。研究指出,尿白蛋白排泄率(UAER)是老年2型糖尿病患者并发冠心病最主要的危险因素,伴微量白蛋白尿的老年2型糖尿病患者冠心病患病风险增加,且严重程度增加;UAER与老年2型糖尿病患者冠心病的发生及冠脉病变严重程度呈正相关,为其独立影响因素。该论文发表于2012年第4期《中华老年医学杂志》上。

  回顾性分析我院住院行冠状动脉(冠脉)造影检查的60岁以上老年2型糖尿病患者503例临床资料,测定糖尿病患者尿白蛋白排泄率( urinary albuminexcretion rate,UAER)等指标,采用Gensini系统对冠脉血管病变程度进行评分.。

  结果 第1~7主成分的特征值均大于1,累计贡献率为64.6%;第1~4主成分分别为UAER、血脂、血压、尿酸,贡献率分别为14.1%、11.8%、10.2%、8.7%;第5~7主成分均属血糖,累计贡献率为19.8%。

 



    

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1976318, encodeId=0d1219e631891, content=<a href='/topic/show?id=1bc680101d7' target=_blank style='color:#2F92EE;'>#老年2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80101, encryptionId=1bc680101d7, topicName=老年2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jun 01 10:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077945, encodeId=f8ba20e7945fd, content=<a href='/topic/show?id=91104e474b5' target=_blank style='color:#2F92EE;'>#尿白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47474, encryptionId=91104e474b5, topicName=尿白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9dd613, createdName=xxxx1049, createdTime=Mon May 06 10:22:00 CST 2013, time=2013-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757541, encodeId=0dcc1e5754130, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Thu Sep 20 18:22:00 CST 2012, time=2012-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743840, encodeId=92ed1e4384029, content=<a href='/topic/show?id=9b185665065' target=_blank style='color:#2F92EE;'>#排泄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56650, encryptionId=9b185665065, topicName=排泄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d01c35235377, createdName=维他命, createdTime=Sun Aug 26 01:22:00 CST 2012, time=2012-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304572, encodeId=b54a13045e2e9, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Aug 12 00:22:00 CST 2012, time=2012-08-12, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1976318, encodeId=0d1219e631891, content=<a href='/topic/show?id=1bc680101d7' target=_blank style='color:#2F92EE;'>#老年2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80101, encryptionId=1bc680101d7, topicName=老年2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jun 01 10:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077945, encodeId=f8ba20e7945fd, content=<a href='/topic/show?id=91104e474b5' target=_blank style='color:#2F92EE;'>#尿白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47474, encryptionId=91104e474b5, topicName=尿白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9dd613, createdName=xxxx1049, createdTime=Mon May 06 10:22:00 CST 2013, time=2013-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757541, encodeId=0dcc1e5754130, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Thu Sep 20 18:22:00 CST 2012, time=2012-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743840, encodeId=92ed1e4384029, content=<a href='/topic/show?id=9b185665065' target=_blank style='color:#2F92EE;'>#排泄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56650, encryptionId=9b185665065, topicName=排泄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d01c35235377, createdName=维他命, createdTime=Sun Aug 26 01:22:00 CST 2012, time=2012-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304572, encodeId=b54a13045e2e9, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Aug 12 00:22:00 CST 2012, time=2012-08-12, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1976318, encodeId=0d1219e631891, content=<a href='/topic/show?id=1bc680101d7' target=_blank style='color:#2F92EE;'>#老年2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80101, encryptionId=1bc680101d7, topicName=老年2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jun 01 10:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077945, encodeId=f8ba20e7945fd, content=<a href='/topic/show?id=91104e474b5' target=_blank style='color:#2F92EE;'>#尿白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47474, encryptionId=91104e474b5, topicName=尿白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9dd613, createdName=xxxx1049, createdTime=Mon May 06 10:22:00 CST 2013, time=2013-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757541, encodeId=0dcc1e5754130, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Thu Sep 20 18:22:00 CST 2012, time=2012-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743840, encodeId=92ed1e4384029, content=<a href='/topic/show?id=9b185665065' target=_blank style='color:#2F92EE;'>#排泄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56650, encryptionId=9b185665065, topicName=排泄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d01c35235377, createdName=维他命, createdTime=Sun Aug 26 01:22:00 CST 2012, time=2012-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304572, encodeId=b54a13045e2e9, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Aug 12 00:22:00 CST 2012, time=2012-08-12, status=1, ipAttribution=)]
    2012-09-20 丁鹏鹏
  4. [GetPortalCommentsPageByObjectIdResponse(id=1976318, encodeId=0d1219e631891, content=<a href='/topic/show?id=1bc680101d7' target=_blank style='color:#2F92EE;'>#老年2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80101, encryptionId=1bc680101d7, topicName=老年2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jun 01 10:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077945, encodeId=f8ba20e7945fd, content=<a href='/topic/show?id=91104e474b5' target=_blank style='color:#2F92EE;'>#尿白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47474, encryptionId=91104e474b5, topicName=尿白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9dd613, createdName=xxxx1049, createdTime=Mon May 06 10:22:00 CST 2013, time=2013-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757541, encodeId=0dcc1e5754130, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Thu Sep 20 18:22:00 CST 2012, time=2012-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743840, encodeId=92ed1e4384029, content=<a href='/topic/show?id=9b185665065' target=_blank style='color:#2F92EE;'>#排泄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56650, encryptionId=9b185665065, topicName=排泄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d01c35235377, createdName=维他命, createdTime=Sun Aug 26 01:22:00 CST 2012, time=2012-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304572, encodeId=b54a13045e2e9, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Aug 12 00:22:00 CST 2012, time=2012-08-12, status=1, ipAttribution=)]
    2012-08-26 维他命
  5. [GetPortalCommentsPageByObjectIdResponse(id=1976318, encodeId=0d1219e631891, content=<a href='/topic/show?id=1bc680101d7' target=_blank style='color:#2F92EE;'>#老年2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80101, encryptionId=1bc680101d7, topicName=老年2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sat Jun 01 10:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077945, encodeId=f8ba20e7945fd, content=<a href='/topic/show?id=91104e474b5' target=_blank style='color:#2F92EE;'>#尿白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47474, encryptionId=91104e474b5, topicName=尿白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9dd613, createdName=xxxx1049, createdTime=Mon May 06 10:22:00 CST 2013, time=2013-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757541, encodeId=0dcc1e5754130, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Thu Sep 20 18:22:00 CST 2012, time=2012-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743840, encodeId=92ed1e4384029, content=<a href='/topic/show?id=9b185665065' target=_blank style='color:#2F92EE;'>#排泄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56650, encryptionId=9b185665065, topicName=排泄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d01c35235377, createdName=维他命, createdTime=Sun Aug 26 01:22:00 CST 2012, time=2012-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304572, encodeId=b54a13045e2e9, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Aug 12 00:22:00 CST 2012, time=2012-08-12, status=1, ipAttribution=)]
    2012-08-12 珙桐

相关资讯

Circulation:合理使用非营养性甜味剂或有益健康

7月9日,ADA和AHA联合发表声明称,只有在人们不增加额外能量摄入,并把非营养性甜味剂(NNS)作为补充食品使用时,NNS才会对人体有益处。然而,NNS替代饮料或食品中的能量甜味剂,能否减少添加糖或碳水化合物的摄入以及在改善食欲、平衡能量、保持正常体重或改善心脏代谢危险因素等方面获益,目前尚无足够的证据。(Circulation.2012年7月9日在线版)   &n

NEJM:糖尿病患者服用鱼油补充剂不能降低心脏病风险

  日前《新英格兰医学杂志》的一项研究指出,如果你有糖尿病或糖尿病前期,鱼油补充剂可能无法降低心脏病风险。   鱼油补充剂含有omega-3(n-3)脂肪酸,美国心脏学会表示,n-3脂肪酸已被证明对心脏病高风险者的心脏有益。但在这项研究中发现,2型糖尿病或糖尿病前期患者服用N-3脂肪酸补充剂,心梗或中卒死亡的风险与没有服用者一样。     这项研究是针对约12536例糖尿病或糖尿病前期的心脏病

Diabetes Care :睡眠不佳主诉与非糖尿病者胰岛素抵抗有关

  芬兰研究者进行的PPP-Botnia研究表明,睡眠不佳主诉与胰岛素抵抗有关,胰岛素抵抗的可能性随着睡眠不佳主诉的次数增多而增加,但与胰岛素分泌不足无关。该研究结果2012年7月26日在线发表于《糖尿病护理》杂志。   既往研究表明,睡眠障碍和个体的睡眠不佳主诉与2型糖尿病危险升高有关。但非2型糖尿病患者的胰岛素抵抗和胰岛素分泌证据缺乏。研究者对年龄为18~75岁的男女两个性别共796例受试者

Cell Metab:治疗糖尿病和肥胖症的新靶标

近日,圣路易斯华盛顿大学医学院研究人员发现可用于治疗糖尿病和肥胖症的潜在靶标。通过研究老鼠,他们发现,当目标蛋白被抑制后,动物变得对胰岛素更敏感,不太容易发胖,甚至当他们吃高脂肪的饮食时亦是如此。 该研究结果发表在Cell Metabolism杂志上。研究人员研究了身体如何从食物如碳水化合物中制造产生脂肪,这一过程需要一种叫做脂肪酸合成酶(FAS)的酶。老鼠基因改造后脂肪细胞中不能产生FAS,所

美国CDC Trudy Murphy博士:糖尿病成人患者接种乙肝疫苗新建议

         大家好,我是疾病控制和预防中心(CDC, Centers for Disease Control and Prevention)的病毒性肝炎疫苗研究和政策小组的主管Trudy Murphy博士。今天我将向大家讲解糖尿病成人患者接种疫苗预防乙型肝炎病毒的感染的新建议,该建议适用于1型和2型糖尿病的成人患者。   &n

糖尿病人群基线高敏C反应蛋白3.0mg/L新发心脑血管事件风险高

  河北联合大学附属开滦医院与河北遵化市人民医院和唐山市第三医院联合研究发现,基线高敏C反应蛋白(hsC-RP)>3.0mg/L增加无高血压病史的糖尿病人群新发心脑血管事件的风险。 相关论文发表于2012年第6期《中国糖尿病杂志》。   研究者们采用前瞻性队列研究方法,以参加健康体检的101510名开滦集团职工中FPG≥7.0mmol/L或已确诊为糖尿病,正在使用降糖药物的297