Brit J Cancer:咖啡类型与消化系统癌症风险的关系

2019-05-06 xing.T 网络

该研究的证据表明,咖啡摄入量与肝细胞癌呈负相关,而速溶咖啡与咖啡粉两种类型相似。

咖啡摄入与肝癌之间存在反向关联,但与其他消化系统肿瘤的相关性尚不清楚。以前很少有研究在一个队列中调查过咖啡类型(特别是速溶咖啡或咖啡粉)与一系列消化系统肿瘤类型的关系。近日,肿瘤领域权威杂志British Journal of Cancer上发表了一篇研究文章,研究人员在基于人群的队列中调查了按类型的咖啡摄入与消化系统癌症风险的关系。

英国生物银行捕获了自我报告的咖啡摄入和癌症登记中心记录的消化系统癌症患者。研究人员使用Cox回归计算风险比(HR)和95%CI。并通过剂量反应和咖啡类型(脱咖啡因、速溶和研磨)研究了每种类型的消化系统癌症的风险与咖啡摄入的关联。

在超过7.5年的随访中,在471779名参与者中3567名患者发生消化系统癌症。其中88例肝细胞癌,并且在咖啡饮用者中可见其与肝细胞癌有明显的负相关性(HR为0.50,95%CI为0.29,0.87),速溶(HR为0.51,95%CI为0.28,0.93)和咖啡粉(HR为0.47,95%CI为0.20,1.08)相似。研究人员没有观察到咖啡饮用者中其他消化系统癌症的风险显著降低。

该研究的证据表明,咖啡摄入量与肝细胞癌呈负相关,而速溶咖啡与咖啡粉两种类型相似。 

原始出处:

Kim Tu Tran,et al.Coffee consumption by type and risk of digestive cancer: a large prospective cohort study.British Journal of Cancer. 2019.https://www.nature.com/articles/s41416-019-0465-y

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    2019-05-08 ms8630568411788502

    学习了

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    2019-05-08 ms8630568411788502

    学习了

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    2019-05-07 医者仁心5538

    学习了

    0