JAHA:基底动脉直径的变化与心血管事件发生呈负相关

2019-02-25 不详 MedSci原创

基底动脉(BA)的扩张被认为是心血管事件(CVEs)发生的预测因子,然而 ,BA直径的纵向变化(ΔBA)是否与CVEs相关尚不清楚。首先,本研究对493例患者采用时间依赖性Cox比例风险模型进行分析,以评估ΔBA和CVES之间的相关性。其次,通过线性回归分析,本研究评估了164名接受长期随访磁共振成像的患者的纵向ΔBA。经过平均8.7年时间的随访,有105例患者发展为CVEs,较小的Δba与高CV

基底动脉(BA)的扩张被认为是血管事件(CVEs)发生的预测因子,然而 ,BA直径的纵向变化(ΔBA)是否与CVEs相关尚不清楚。

首先,本研究对493例患者采用时间依赖性Cox比例风险模型进行分析,以评估ΔBA和CVES之间的相关性。其次,通过线性回归分析,本研究评估了164名接受长期随访磁共振成像的患者的纵向ΔBA。经过平均8.7年时间的随访,有105例患者发展为CVEs,较小的Δba与高CVES发生率独立相关(HR:0.36; 95% CI, 0.16–0.78; P=0.010; n=493)。平均间隔9.4年后,ΔBA的平均大小为0.41±0.46?mm。另外,BA扩张的进展与男性相关,但与初始BA直径和胎儿型Willis环呈负相关(n=164)。

研究结果显示,基底动脉的直径会随着时间推移而增大,BA直径的纵向变化与血管事件的发生呈负相关。

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    2019-02-27 zhaohui6731
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    2019-02-27 hmwwww

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