Clin Respir J:过敏性鼻炎和睡眠呼吸暂停综合征儿童共有的和特异的风险因子和临床生物标记研究

2019-12-23 AlexYang MedSci原创

鼻炎和睡眠呼吸暂停综合征(OSAS)是不同的疾病,但是具有相似的风险因子。最近,有研究人员比较了鼻炎和OSAS儿童中的风险因子和临床生物标记情况。研究是一个代表性的研究,包括了3917名儿童(4-13岁)。研究发现,OSAS和鼻炎在研究群体中的患病率分别为4.0%和43.5%。身体质量指数(P<0.001)和早熟(P=0.016)与OSAS显著相关,而与鼻炎没有相关性。父母更高的教育水平和收

鼻炎和睡眠呼吸暂停综合征(OSAS)是不同的疾病,但是具有相似的风险因子。最近,有研究人员比较了鼻炎和OSAS儿童中的风险因子和临床生物标记情况。

研究是一个代表性的研究,包括了3917名儿童(4-13岁)。研究发现,OSAS和鼻炎在研究群体中的患病率分别为4.0%和43.5%。身体质量指数(P<0.001)和早熟(P=0.016)与OSAS显著相关,而与鼻炎没有相关性。父母更高的教育水平和收入增加了鼻炎的风险,但是减少了OSAS的风险。有更多的姐妹和剖腹产减少了鼻炎的风险,但是居住在新房子能够增加鼻炎的风险。怀孕期间居住在距离交通主干道近的能够显著的增加OSAS风险。男性、霉菌接触增加和第一个孩子均能够增加OSAS和鼻炎的风险。NLR在OSAS患者中要比过敏性鼻炎患者更高(P=0.001)。

最后,研究人员指出,OSAS和鼻炎具有共有的风险因子,而其他因子与上述2种疾病具有负相关性。他们的结果表明了在预防鼻炎和OSAS中可以采用不同的策略。

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