JACC:经导管主动脉瓣置换术后感染性心内膜炎

2020-06-17 MedSci原创 MedSci原创

感染性心内膜炎可能影响经导管主动脉瓣置换术(TAVR)后的患者。本研究旨在提供TAVR术后感染性心内膜炎的发病率、微生物类型和预后的详细资料。

感染性心内膜炎可能影响经导管主动脉瓣置换术(TAVR)后的患者。本研究旨在提供TAVR术后感染性心内膜炎的发病率、微生物类型和预后的详细资料。

本研究纳入分析了来自瑞士15家医院的7203名接受TAVR手术的患者,经过平均14832个人年的随访,有149名患者发生有感染性心内膜炎,围手术期(术后<100天)、早期(术后100天-1年)和晚期(术后>1年)的心内膜炎发生率分别是2.59, 0.71和0.40每100人年。在早期心内膜炎患者中,肠球菌是最常见的病原菌(30.1%)。在围手术期心内膜炎患者中,47.9%的患者有一种对围手术期抗生素预防不敏感的病原体。年轻、男性、缺乏预扩张和不在杂交手术室是心内膜炎发生的独立危险因素。另外,患有心内膜炎的患者死亡率和卒中发生率更高。

研究结果显示,TAVR术后感染性心内膜炎最常发生在早期,通常由肠球菌引起,会增加患者死亡和卒中发生风险。

原始出处:

Stefan S et al.Infective Endocarditis After Transcatheter Aortic Valve Replacement.JACC.2020 June.

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    2020-08-20 hbwxf
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beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Fri Jun 19 02:28:40 CST 2020, time=2020-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350750, encodeId=1f0c1350e507a, content=<a href='/topic/show?id=a32d508e8c3' target=_blank style='color:#2F92EE;'>#心内膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50878, encryptionId=a32d508e8c3, topicName=心内膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Jun 19 02:28:40 CST 2020, time=2020-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367221, 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19 02:28:40 CST 2020, time=2020-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1510308, encodeId=0b37151030808, content=<a href='/topic/show?id=e9bce8254ef' target=_blank style='color:#2F92EE;'>#经导管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78254, encryptionId=e9bce8254ef, topicName=经导管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93e010191378, createdName=lsj631, createdTime=Fri Jun 19 02:28:40 CST 2020, time=2020-06-19, status=1, ipAttribution=)]
    2020-06-18 yxch48
  5. 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  6. 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  7. 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    2020-06-19 lsj631

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