AAHFN 2016:利尿可以改善HF患者的认知功能

2016-06-27 Mechront 译 MedSci原创

第十二届AAHFN年会称,有效利尿可能会改善HF患者的认知功能。约翰霍普金斯湾景医学中心的Tanya Simmons博士和同事对109名HF患者进行了初始的预利尿试验,66例患者完成了随访。通过简易精神状态检查来评估记忆、注意力和语言等;一个钉板检查执行功能和连线测验B检查视觉注意、任务切换、视觉搜索的速度、思维的灵活性和执行功能。对18名参与者在初始和后续测试过程中测定C-反应蛋白水平。数据显示

第十二届AAHFN年会称,有效利尿可能会改善HF患者的认知功能。

约翰霍普金斯湾景医学中心的Tanya Simmons博士和同事对109名HF患者进行了初始的预利尿试验,66例患者完成了随访。通过简易精神状态检查来评估记忆、注意力和语言等;一个钉板检查执行功能和连线测验B检查视觉注意、任务切换、视觉搜索的速度、思维的灵活性和执行功能。对18名参与者在初始和后续测试过程中测定C-反应蛋白水平。

数据显示,后利尿试验患者的平均年龄为65.5岁,其中48.48%为女性。46.97%的患者有中度至重度周围水肿;16.67%的患者有中度至重度肺水肿。

初始随访数据显示,GP主导领域和非主导领域得分更低的风险分别为3.7倍和4.6倍。HFpEF患者与HFrEF患者相比,简易精神状态检查得分更低。

利尿后以下4个结局的β得分均有所改善:简易精神状态检查,0.2;GP主导,18.2;GP非主导,4.4;连线测验B,29.5。亚组分析发现,C-反应蛋白的减少与简易精神状态检查的改善有关(P = .014)。

这项研究表明,心衰患者往往表现出认知能力的受损。数据还表明,有效的利尿可以减少肺和外周水肿,进而改善认知功能。认知状态可能是慢性心力衰竭患者未来教育和自我护理管理干预的一个考虑因素。在以后还需要更多的相关研究。

原始出处:

Simmons T, et al. Oral Abstracts 2. Presented at: American Association of Heart Failure Nurses Annual Meeting; June 23-25, 2016; Scottsdale, Ariz.

Diuresis improves cognitive impairment in patients with HF.Healio.June 24, 2016

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    2017-04-16 lemon985

    研究好奇怪

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=187782, encodeId=55d918e7821a, content=研究好奇怪, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca432042642, createdName=lemon985, createdTime=Sun Apr 16 00:40:17 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2024667, encodeId=e7b6202466ed7, content=<a href='/topic/show?id=5c4e214048' target=_blank style='color:#2F92EE;'>#AHF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2140, encryptionId=5c4e214048, topicName=AHF)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cd7162, createdName=nakerunner, createdTime=Thu Jan 26 22:20:00 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146106, encodeId=a5041461063f, content=好文,值得推荐。, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Oct 11 22:38:33 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91438, encodeId=fcf39143865, content=利尿剂的功能越来越多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Jun 28 13:03:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91427, encodeId=2a2c9142ea1, content=新的认识 学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9f861634573, createdName=tiantian569, createdTime=Tue Jun 28 11:35:00 CST 2016, time=2016-06-28, status=1, ipAttribution=)]
    2017-01-26 nakerunner
  3. [GetPortalCommentsPageByObjectIdResponse(id=187782, encodeId=55d918e7821a, content=研究好奇怪, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca432042642, createdName=lemon985, createdTime=Sun Apr 16 00:40:17 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2024667, encodeId=e7b6202466ed7, content=<a href='/topic/show?id=5c4e214048' target=_blank style='color:#2F92EE;'>#AHF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2140, encryptionId=5c4e214048, topicName=AHF)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cd7162, createdName=nakerunner, createdTime=Thu Jan 26 22:20:00 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146106, encodeId=a5041461063f, content=好文,值得推荐。, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Oct 11 22:38:33 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91438, encodeId=fcf39143865, content=利尿剂的功能越来越多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Jun 28 13:03:00 CST 2016, time=2016-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91427, encodeId=2a2c9142ea1, content=新的认识 学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9f861634573, createdName=tiantian569, createdTime=Tue Jun 28 11:35:00 CST 2016, time=2016-06-28, status=1, ipAttribution=)]
    2016-10-11 ylzr123

    好文,值得推荐。

    0

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    2016-06-28 1df01bccm39(暂无匿称)

    利尿剂的功能越来越多了

    0

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    2016-06-28 tiantian569

    新的认识 学习到了

    0

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