BMJ子刊:较高强度的运动或抵消睡眠不足带来的健康危害

2021-06-30 K.K MedSci原创

轻度运动-睡眠不佳组合的参与者具有较高的全因、总心血管疾病、冠心病和肺癌的死亡风险。

6月29日,英国运动医学杂志在线发表了一项长期研究表明,达到或高于每周推荐量的身体活动水平可能会抵消与睡眠质量差引起的健康危害。

Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality,British Journal of Sports Medicine(2021).DOI: 10.1136/bjsports-2021-104046

之前的研究认为:睡眠时间与全因、心血管疾病和癌症的死亡率呈曲线关系(U形),每晚7-8小时睡眠的人中观察到的疾病风险最低、以及睡眠质量差、睡眠不足或睡得太多与死亡风险增加有关。

2018年6月,Sleep上发表4994人随访11.4年的睡眠心脏健康研究发现:睡眠时间不足和睡眠质量差结合与心血管疾病的风险有关。

然而,低水平运动可能通过改善代谢(如减少胰岛素抵抗)、保持稳定的昼夜节律、健康的睡眠模式、提高能量消耗来改善健康状况。

本文研究人员调查了轻度运动和综合睡眠评分与全因死亡、特异性心血管疾病、心血管死亡风险之间的关系,共纳入380055名参与者(55.9±8.1岁,55%为女性)。其中,平均随访时间为(11.1±1.2)年,有15503例全因死亡(4095例心血管疾病和9064例癌症,包括1932例冠心病,359例出血性中风,450例缺血性中风和1595例肺癌)。

56%参与者有健康的睡眠,其次是有中等(42%)或差的睡眠(3%)。年轻、女性、较瘦、面临较少经济问题、有较高的蔬菜和水果摄入量、坐得少、没有精神健康问题、从不吸烟、受雇于非轮班工作、喝较少的酒和有较多的轻度运动的参与者,往往有较健康的睡眠水平。

按睡眠分类的参与者特征

睡眠、轻度运动与死亡风险的关系

在全因、总心血管疾病和缺血性中风的死亡风险中,有睡眠较差现象。在对混杂因素调整后,相对于健康睡眠,不良、睡眠质量一般与全因死亡和心血管死亡风险有关。睡眠不佳与缺血性中风进一步相关,而睡眠一般与冠心病进一步相关。

与较高的身体活动的参与者相比,其他活动水平的参与者全因死亡率风险逐渐增加(中等水平HR为1.05;低水平HR为1.08;无中度至剧烈运动HR为1.25)。除出血性中风外,没有中度至剧烈运动的人在其他疾病方面的风险也较高(总心血管疾病HR1.31;总癌症HR1.16;冠心病HR1.35;缺血性中风HR1.38;肺癌HR1.35)。

调整一些参数后,除出血性中风外,无中度至剧烈运动参与者有较高的死亡风险,与睡眠不佳相互影响的参与者有最高的风险(对于全因死亡HR 1.57;总心血管疾HR 1.67;总癌症HR 1.45;冠心病HR 1.59;缺血性中风HR2.96;肺癌HR 1.91)。轻度运动-睡眠不佳组合的参与者具有较高的全因、总心血管疾病、冠心病和肺癌的死亡风险。

睡眠不好与全因死亡和特殊死亡风险较高有关,这些风险在运动不足的参与者中加剧了,达到目前运动指南的较低门槛(600 MET-分/周)可以消除睡眠不佳与死亡率的有害联系。

原始出处:

https://bjsm.bmj.com/content/early/2021/05/25/bjsports-2021-104046.long

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    2022-02-06 gaoxiaoe
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    2021-07-08 乌拉小草

    可以

    0

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    2021-07-02 aids219
  5. [GetPortalCommentsPageByObjectIdResponse(id=1973479, encodeId=731219e34791d, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Apr 02 01:53:53 CST 2022, time=2022-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849280, encodeId=f93e1849280ba, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Feb 06 00:53:53 CST 2022, time=2022-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997424, encodeId=deff99e42402, content=可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/96b10214fe8f4a039febb3ea9891a8aa/df59dd3a997242479937a4f3feae3b05.jpg, createdBy=052c5526600, createdName=乌拉小草, createdTime=Thu Jul 08 08:47:34 CST 2021, time=2021-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604052, encodeId=f7891604052f4, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Fri Jul 02 01:53:53 CST 2021, time=2021-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978765, encodeId=45629e87650c, content=OMG, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210701/7aeaf4b9c36f43f2a16c9d70777d9ab8/57ab422ee66c4a89a732809040711f06.jpg, createdBy=bdfe5483549, createdName=Svana, createdTime=Thu Jul 01 21:14:46 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978452, encodeId=82579e8452db, content=这个好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210620/b2ef2e99ec694387b63ad8f7e6e8de5c/39dd8c0bf4c047409733087eb557bcfb.jpg, createdBy=e6495527783, createdName=冰溪之鱼2, createdTime=Thu Jul 01 02:47:57 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978438, encodeId=a60b9e843882, content=睡眠量与死亡密切相关, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2020/02/20/44e485222679b3a7b0d5676ca7443126.jpg, createdBy=ef735089224, createdName=随风1991, createdTime=Thu Jul 01 00:34:43 CST 2021, time=2021-07-01, status=1, ipAttribution=)]
    2021-07-01 Svana

    OMG

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1973479, encodeId=731219e34791d, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Apr 02 01:53:53 CST 2022, time=2022-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849280, encodeId=f93e1849280ba, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Feb 06 00:53:53 CST 2022, time=2022-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997424, encodeId=deff99e42402, content=可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/96b10214fe8f4a039febb3ea9891a8aa/df59dd3a997242479937a4f3feae3b05.jpg, createdBy=052c5526600, createdName=乌拉小草, createdTime=Thu Jul 08 08:47:34 CST 2021, time=2021-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604052, encodeId=f7891604052f4, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Fri Jul 02 01:53:53 CST 2021, time=2021-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978765, encodeId=45629e87650c, content=OMG, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210701/7aeaf4b9c36f43f2a16c9d70777d9ab8/57ab422ee66c4a89a732809040711f06.jpg, createdBy=bdfe5483549, createdName=Svana, createdTime=Thu Jul 01 21:14:46 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978452, encodeId=82579e8452db, content=这个好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210620/b2ef2e99ec694387b63ad8f7e6e8de5c/39dd8c0bf4c047409733087eb557bcfb.jpg, createdBy=e6495527783, createdName=冰溪之鱼2, createdTime=Thu Jul 01 02:47:57 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978438, encodeId=a60b9e843882, content=睡眠量与死亡密切相关, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2020/02/20/44e485222679b3a7b0d5676ca7443126.jpg, createdBy=ef735089224, createdName=随风1991, createdTime=Thu Jul 01 00:34:43 CST 2021, time=2021-07-01, status=1, ipAttribution=)]
    2021-07-01 冰溪之鱼2

    这个好

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1973479, encodeId=731219e34791d, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Apr 02 01:53:53 CST 2022, time=2022-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849280, encodeId=f93e1849280ba, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Feb 06 00:53:53 CST 2022, time=2022-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997424, encodeId=deff99e42402, content=可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/96b10214fe8f4a039febb3ea9891a8aa/df59dd3a997242479937a4f3feae3b05.jpg, createdBy=052c5526600, createdName=乌拉小草, createdTime=Thu Jul 08 08:47:34 CST 2021, time=2021-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604052, encodeId=f7891604052f4, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Fri Jul 02 01:53:53 CST 2021, time=2021-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978765, encodeId=45629e87650c, content=OMG, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210701/7aeaf4b9c36f43f2a16c9d70777d9ab8/57ab422ee66c4a89a732809040711f06.jpg, createdBy=bdfe5483549, createdName=Svana, createdTime=Thu Jul 01 21:14:46 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978452, encodeId=82579e8452db, content=这个好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210620/b2ef2e99ec694387b63ad8f7e6e8de5c/39dd8c0bf4c047409733087eb557bcfb.jpg, createdBy=e6495527783, createdName=冰溪之鱼2, createdTime=Thu Jul 01 02:47:57 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978438, encodeId=a60b9e843882, content=睡眠量与死亡密切相关, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2020/02/20/44e485222679b3a7b0d5676ca7443126.jpg, createdBy=ef735089224, createdName=随风1991, createdTime=Thu Jul 01 00:34:43 CST 2021, time=2021-07-01, status=1, ipAttribution=)]
    2021-07-01 随风1991

    睡眠量与死亡密切相关

    0

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