Clin Exp Rheumatol:根据人口学、脑脊髓和影像学特征区分神经结节病与原发性中枢神经系统血管炎

2020-01-20 xiangting MedSci原创

这些发现表明,MRI可以成为区分PACNS与NS的有效工具。需要进行更大样本量的随访研究以验证这项研究结果。

神经结节病(NS)和中枢神经系统原发性血管炎(PACNS)是影响中枢神经系统的炎性疾病,具有重叠的临床和病理特征。鉴于治疗不同,区分这些疾病很重要。这项研究旨在比较这两种疾病的人口学、CSFMRI特征。

从电子病历提取发病时的临床CSF和实验室检查特征。由两名神经放射科医生盲评发病时的脑和/或脊髓MRI检查。记录每名患者有关硬脑脊膜和软脑膜、基底脑膜、颅神经,脑灰质和白质以及脊髓受累的数据。

该研究纳入78PACNS患者和25NS患者。PACNSNS患者的平均年龄分别为43.7岁(±16.7)和43.6岁(±12.5)。发现非裔美国人与NS诊断有关,而不是PACNSPACNS患者大脑受累更常见,而NS患者脊髓、基底脑膜和颅神经受累更常见。

这些发现表明,MRI可以成为区分PACNSNS的有效工具。需要进行更大样本量的随访研究以验证这项研究结果。

原始出处:

D. Saygin. Differentiation between neurosarcoidosis and primary central nervous system vasculitis based on demographic, cerebrospinal and imaging features. Clin Exp Rheumatol. January 2020.

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    2020-01-20 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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