Gut:胃肠道感染后肠易激综合征和慢性疲劳的发生率

2017-06-11 zhangfan MedSci原创

精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳

近日研究人员就感染后肠易激综合征(IBS)常规门诊治疗进行研究,比较不同类型的胃肠道感染及并发症对患者身心的影响。

该回顾性队列研究收集德国巴伐利亚患者的医疗保险资料,无肠功能紊乱史,2005-13年间首次确诊胃肠感染患者入选本次研究,根据感染类型进行分类,对患者心理障碍(抑郁、焦虑、应激障碍)进行评估。利用比例风险回归模型评估胃肠道感染和心理障碍的风险。慢性疲劳综合征(CFS)为评定的比较结果。

研究共508278名首次感染患者及1016556名对照患者参与。研究发现,所有的胃肠感染均导致IBS(HR 2.19–4.25) 和CFS(HR 1.35–1.82)风险增加。先前的心理障碍是显著的IBS(HR:1.73)和CFS(HR:2.08)的危险因素。女性受胃肠感染和心理障碍的影响更为显著。

精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳。

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    2017-06-13 tamgche
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    2017-06-12 1e0f8808m18(暂无匿称)

    精神压力大是肠易激惹综合征发病因素。

    0

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encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Jun 13 01:19:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459978, encodeId=7d9814599e811, content=<a href='/topic/show?id=f1c78168032' target=_blank style='color:#2F92EE;'>#肠道感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81680, encryptionId=f1c78168032, topicName=肠道感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69b16221893, createdName=medscijoin, createdTime=Tue Jun 13 01:19:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209626, encodeId=dbf9209626d6, content=精神压力大是肠易激惹综合征发病因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Mon Jun 12 06:10:38 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209431, encodeId=c5fe20943137, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sun Jun 11 14:29:58 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209414, encodeId=4e532094144b, content=压力山大作息不规律影响大, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Sun Jun 11 13:52:02 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209409, encodeId=ebae2094096b, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Jun 11 13:35:52 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209392, encodeId=a60f20939294, content=精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdDM6bDRvRy9LKfO8ia4GwNGt3Ueq5JR97QQCQhBViaxE2XtljmmLNh2ID4wJxbib1gTv4O0eiauaZcBU/0, createdBy=77742061279, createdName=1381edfeefm, createdTime=Sun Jun 11 12:15:24 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 三生有幸9135

    学习一下谢谢分享

    0

  8. 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content=精神压力大是肠易激惹综合征发病因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Mon Jun 12 06:10:38 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209431, encodeId=c5fe20943137, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sun Jun 11 14:29:58 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209414, encodeId=4e532094144b, content=压力山大作息不规律影响大, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Sun Jun 11 13:52:02 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209409, encodeId=ebae2094096b, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Jun 11 13:35:52 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209392, encodeId=a60f20939294, content=精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdDM6bDRvRy9LKfO8ia4GwNGt3Ueq5JR97QQCQhBViaxE2XtljmmLNh2ID4wJxbib1gTv4O0eiauaZcBU/0, createdBy=77742061279, createdName=1381edfeefm, createdTime=Sun Jun 11 12:15:24 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 楠博One

    压力山大作息不规律影响大

    0

  9. 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content=精神压力大是肠易激惹综合征发病因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Mon Jun 12 06:10:38 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209431, encodeId=c5fe20943137, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sun Jun 11 14:29:58 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209414, encodeId=4e532094144b, content=压力山大作息不规律影响大, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Sun Jun 11 13:52:02 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209409, encodeId=ebae2094096b, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Jun 11 13:35:52 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209392, encodeId=a60f20939294, content=精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdDM6bDRvRy9LKfO8ia4GwNGt3Ueq5JR97QQCQhBViaxE2XtljmmLNh2ID4wJxbib1gTv4O0eiauaZcBU/0, createdBy=77742061279, createdName=1381edfeefm, createdTime=Sun Jun 11 12:15:24 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 中医痴

    不错的,学习了,谢谢分享!

    0

  10. 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    2017-06-11 1381edfeefm

    精神心理疾病及肠胃感染是肠易激综合征主要风险因素。非特异性胃肠道感染易导致感染后肠易激综合征并引发慢性疲劳。

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