J Endod:牙髓再生治疗牙根发育成熟牙齿髓腔内再生组织的组织学评估

2019-09-19 MedSci MedSci原创

近来,牙髓再生疗法(REPs)已应用于罹患根尖周炎的成熟恒牙的治疗中。尽管动物学的REPs研究已得到一些组织病理学发现,但在人发育成熟牙齿中的研究还很少。到目前为止,对于类似牙齿根管内组织形成的特性还未可知。这篇报告描述的是一例人发育成熟上颌切牙因外伤导致髓腔暴露后成功施以REPs后的再生组织的组织学观察。 1名20岁的女性患者来到作者诊所要求治疗上颌中切牙(#8和#9)。切牙罹患根尖周炎。

近来,牙髓再生疗法(REPs)已应用于罹患根尖周炎的成熟恒牙的治疗中。尽管动物学的REPs研究已得到一些组织病理学发现,但在人发育成熟牙齿中的研究还很少。到目前为止,对于类似牙齿根管内组织形成的特性还未可知。这篇报告描述的是一例人发育成熟上颌切牙因外伤导致髓腔暴露后成功施以REPs后的再生组织的组织学观察。


120岁的女性患者来到作者诊所要求治疗上颌中切牙(#8#9)。切牙罹患根尖周炎。对2颗上颌中切牙施以REPs治疗。治疗结束后的35个月,牙齿发生水平冠折,需要根管治疗及纤维桩修复。于是,小心去除MTA并取出髓腔内已形成的组织,进行常规的组织学免疫化学分析。


组织学结果显示,髓腔内形成了具有活力的组织为纤维结缔组织,包含了骨样组织、血管结构和炎症。这些从发育成熟牙齿获得的组织学结果与之前报道的未发育成熟牙齿中的结果相类似。


结论:基于这篇文章的结果,髓腔内形成的活力组织为纤维结缔组织,它包含骨样组织、血管结构和炎症。这些来自于成熟牙齿的组织学结果与之前未发育成熟牙齿报道的结果相类似。


原始出处:


Arslan H Şahin Y et al. Histologic Evaluation of Regenerated Tissues in the Pulp Spaces of Teeth with Mature Roots at the Time of the Regenerative Endodontic Procedures. J Endod. 2019 Sep 9. pii S0099-2399(19)30582-5. doi 10.1016/j.joen.2019.07.016.


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    2019-10-08 jxrzshh
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    2019-09-21 neurowu
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    2019-09-21 zhouqu_8
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