Neurology:血镁含量异常导致老年人群痴呆风险增加

2017-09-24 zhangfan MedSci原创

研究发现,过高或过低的血清镁水平均导致老年人群各类痴呆风险提高

近日研究人员考察了血清镁水平与各种原因的痴呆和阿尔茨海默病风险之间的关系。

鹿特丹研究是一项基于人口的前瞻性研究,总计9569人参与,研究人员在1997-2008年间对参与者进行了基线血镁浓度检测,所有参与者基线时无痴呆症状。随访至2015年1月,记录参与者的痴呆以及AD症状。研究采用Cox比例风险回归模型评估血清镁与痴呆症之间的关系,调整年龄、性别、研究队列、教育水平、心血管危险因素、肾功能、合并症、其他电解质和利尿剂使用的结果的偏倚。

参与者平均年龄64.9岁,女性占56.6%。平均随访7.8年,其中823人诊断为各种类型的痴呆。研究发现,低(≤0.79 mmol/L)或高(≥0.90 mmol/L)的血镁水平均导致各类型痴呆风险增加(血镁低HR 1.32, 95% CI,1.02-1.69,血镁高HR 1.30, 95% CI 1.02-1.67)。

研究发现,过高或过低的血清镁水平均导致老年人群各类痴呆风险提高。

原始出处:

Brenda C.T. Kieboom et al. Serum magnesium is associated with the risk of dementia. Neurology. September 20 2017.

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    2018-01-16 yinhl1978
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    2017-09-25 meiliwuxian

    脑内有没有变化呢?

    0

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    2017-09-25 138****9420

    学习了.谢谢分享

    0

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    2017-09-24 明崖

    希望多点机制的姐说

    0

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    2017-09-24 131****1460

    学习了受益匪浅

    0

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    2017-09-24 baihao215

    还是希望以后的译文中说一些可能的机制.而不仅仅只是翻译个摘要

    0

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    2017-09-24 1e0f8808m18(暂无匿称)

    血镁水平.影响年智商.

    0

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