Stroke:未确定来源的栓塞性卒中患者具有高风险颈动脉斑块的特征

2019-11-23 xing.T MedSci原创

由此可见,在来源不明的栓塞性卒中患者中,具有高风险特征的斑块在同侧颈动脉中的患病率是对侧颈动脉的5倍,提示与卒中风险有关。

近40%未确定来源的栓塞性卒中患者存在同侧轻度颈动脉狭窄,定义为管腔狭窄小于50%的斑块,并可能无法识别动脉粥样硬化栓塞来源。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在总结有关未确定来源的栓塞性卒中患者中具有高风险特征的轻度颈动脉狭窄频率的数据。

研究人员对Pubmed和Ovid-Embase进行了检索,以查找报告来源不确定的栓塞性卒中中颈动脉斑块成像特征的研究。研究人员使用随机效应荟萃分析汇总了具有高风险特征的同侧和对侧轻度颈动脉狭窄的患病率。

该分析共纳入了八项研究,323名参与者。同侧颈动脉中具有高风险特征的轻度颈动脉狭窄的患病率为32.5%(95%CI为25.3–40.2),而对侧颈动脉为4.6%(95%CI为0.1–13.1)。在同侧颈动脉和对侧颈动脉中发现具有高风险特征斑块的比值比为5.5(95%CI为2.5-12.0)。

由此可见,在来源不明的栓塞性卒中患者中,具有高风险特征的斑块在同侧颈动脉中的患病率是对侧颈动脉的5倍,提示与卒中风险有关。 

原始出处:

Joseph Kamtchum-Tatuene.et al.Carotid Plaque With High-Risk Features in Embolic Stroke of Undetermined Source Systematic Review and Meta-Analysis.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027272

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    2019-11-23 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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