JAHA:门诊利尿剂强化治疗会增加心衰患者死亡风险

2020-07-16 MedSci原创 MedSci原创

失代偿性心力衰竭(HF)住院后死亡率增加,在此期间利尿剂通常会加重,目前尚不清楚在门诊强化利尿剂治疗心力衰竭后风险是如何影响的。

失代偿性心力衰竭(HF)住院后死亡率增加,在此期间利尿剂通常会加重,目前尚不清楚在门诊强化利尿剂治疗心力衰竭后风险是如何影响的。

本研究纳入分析了74990名2001-2016年被诊断心衰的丹麦人群,平均年龄为71岁,女性占36%。随访期间,利尿剂的强化与死亡率的增高相关。强化事件后一年死亡率为18.0%,心衰住院后的为22.6%,对照组为10.4%。在一个校正了年龄、性别、缺血性心脏病、心房颤动、慢性阻塞性肺疾病和糖尿病的多变量Cox模型中,强化事件后1年死亡的危险比为1.75(95%CI,1.66-1.85),心衰住院后1年死亡的危险比为2.28(95%CI,2.16-2.41)。

研究结果显示,对于心衰患者来说,门诊利尿剂的强化治疗会增加患者近2倍的死亡风险。

原始出处:

Christian M et al.One‐Year Mortality After Intensification of Outpatient Diuretic Therapy.JAHA.2020 July.

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    2020-09-05 ms3000001384618595

    如何使用利尿剂,调整剂量,需要心衰患者的密切随访,然后视病情调整

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    2020-07-18 zhaohui6731
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