J Rheumatol:类风湿性关节炎患者骨质疏松症治疗指南的实施效果评估

2020-01-15 xiangting MedSci原创

RA患者对GIOP和PMOP预防不足。该人群骨质疏松症的治疗需要改善。

这项研究旨在评估2003年和2014年法国预防和治疗糖皮质激素引起骨质疏松症(GIOP)指南以及2012年法国治疗绝经后骨质疏松症(PMOP)指南更新是否被用于类风湿性关节炎患者(RA)。

776RA患者(19个中心)进行了横断面研究。收集应用各种指南所需的数据(年龄、性别、泼尼松摄入量、低能量骨折、直系亲属髋部骨折史和骨密度测定)、抗骨质疏松药物以及与指南应用相关的各种因素。

在应该接受抗骨质疏松治疗的患者中,实际接受治疗的比例为22.6%(根据2014年指南),根据2003年指南的比例为27.3%。绝经后妇女为23.6%(根据2012PMOP指南)。与2003GIOP指南相比,应用2014GIOP指南增加了需要治疗的理论患者人数(77vs 53%; p<0.001)。在多因素分析中,根据2014年指南,接受治疗与脊柱T评分≤-2 SD相关。根据2003年指南,与每天体育锻炼不超过30分钟相关;根据PMOP指南,与年龄大、体重指数低且至少1个部位T评分≤-2.5 SD相关。

RA患者对GIOPPMOP预防不足。该人群骨质疏松症的治疗需要改善。

原始出处:

Sandrine Malochet-Guinamand. Evaluation of the Implementation of Guidelines on the Treatment of Osteoporosis in Patients with Rheumatoid Arthritis. J Rheumatol. January 2020.

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    2020-01-17 lmm397
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    2020-01-17 Eleven17
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    2020-01-15 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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