预防接种日:人乳头瘤病毒(宫颈癌)疫苗接种的立场文件:来自欧洲妇科肿瘤学会- 欧洲阴道镜联盟(ESGO - EFC)

2021-01-22 太后殿下 张师前公众号

欧洲妇科肿瘤学会(European Society of Gynaecologic Oncology,ESGO)和欧洲阴道镜联盟(European Federation for Colposcopy,

欧洲妇科肿瘤学会(European Society of Gynaecologic Oncology,ESGO)和欧洲阴道镜联盟(European Federation for Colposcopy,EFC)发布立场文件,强烈推荐针对儿童和青少年开展无性别差异的人乳头瘤病毒(human papilloma virus,HPV)疫苗接种计划,并为年轻人提供HPV 疫苗查漏补种计划。具体内容如下:

1. 临床效力试验数据显示,HPV 疫苗可用于预防宫颈癌、外阴、阴道、肛门癌前期及浸润性宫颈癌;

2. 早期接种疫苗和70% 以上的疫苗覆盖率是减少疾病的最佳方法。高疫苗覆盖率对未接种疫苗的男性和女性具有群体保护作用;

3. 在可行的情况下提供针对年轻人的查漏补种计划,并逐个进行疫苗接种;

4. 在疫苗覆盖率较低的情况下,进行无性别差异接种可提高疫苗的保护作用,最大程度地提高疫苗接种的获益;

5. 有HPV 感染史或曾接受过局部治疗的个体也可以受益于HPV 疫苗接种

6. 基于学校的免疫计划最为有效;

7. 支持针对儿童和青少年的疫苗接种计划,15 岁以下儿童建议接种两剂次,间隔6~12 个月即可,15 岁以上者推荐采用标准三剂次方案;

8. 局部治疗HPV 相关疾病同时接种疫苗,可减少复发,降低HPV 相关疾病发病率;

9. HPV 筛查和疫苗接种是预防宫颈癌最有效的方法。

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E.A. Joura et al. European Journal of Cancer 2019,116:21~26.

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    2021-06-02 tamgche
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