J Endod:壳聚糖-羟基磷灰石前体纳米复合物修饰牙本质基底对封闭剂渗透和拉伸强度的影响

2019-06-03 lishiting MedSci原创

这篇研究的目的是为了评估使用壳聚糖-羟基磷灰石前体(C-HA)纳米复合物处理牙本质后对硅酸三钙封闭剂渗透入牙本质小管深度及其最终拉伸强度(UTS)的影响。

这篇研究的目的是为了评估使用壳聚糖-羟基磷灰石前体(C-HA)纳米复合物处理牙本质后对硅酸三钙封闭剂渗透入牙本质小管深度及其最终拉伸强度(UTS)的影响。研究评估在模拟体液中孵育的C-HA纳米复合物标准膜剂(n = 15)的生物活性,并评估C-HA纳米复合物成分的表面电荷及粒径分布。采用X线衍射及傅里叶变换红外光谱评估矿化潜力,采用扫描电子显微镜进行超微结构分析。在牙本质片(n = 2/group)和牙本质束(n = 10/group)施以次氯酸钠/EDTA和C-HA纳米复合物与否的情况下检测静水接触角和UTS。第2阶段中,采用荧光成像技术(n = 12/group)评估施以C-HA纳米混合物后封闭剂渗透的深度。在距离根尖孔4-和6-mm处计算渗透区域百分比以及平均/最大渗透深度。采用independent samples t检验对接触角测量、力学测试和渗透评估参数数据进行统计学分析,显著性水平设置为P < .05。结果显示,C-HA纳米混合物(2 mg/mL)中多聚阴离子、亲水和非聚集浓缩成分通过形成磷酸盐/碳酸盐结合和所形成矿物质的结晶特质而具有生物活性潜力。施以C-HA纳米

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    2019-06-05 zhangyxzsh
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