Stroke:饮酒方式和缺血性卒中风险

2020-11-07 MedSci原创 MedSci原创

在特定饮酒方式的中年参与者中,缺血性卒中的风险降低,但仅限于早期。考虑到饮酒方式与缺血性卒中之间的长期联系,医师在对患者饮酒的教育方面应保持谨慎。

尽管有研究报道饮酒量与缺血性卒中之间呈J形关联,但尚不清楚饮酒方式的差异是否会影响这种关系。近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,这项研究旨在阐明饮酒方式对中年缺血性卒中的影响。

研究人员使用了来自国家健康保险局的国家样本队列数据,该队列是韩国的大型标准化人口队列。通过结合饮酒的频率和每种情况下的饮酒量来定义五种不同的饮酒方式,即戒酒者不饮酒;I类饮酒者,≤30g/d和<5d/wk;II类饮酒者,≤30g/d和≥5d/wk;III类饮酒者,>30 g/d和<5d/wk;IV类饮酒者,>30 g/d和≥5d/wk。研究人员使用Cox比例风险模型分析了饮酒方式与缺血性卒中发生之间的关联。

该研究共有152469名中年受试者(平均年龄为50.2岁;72285名男性[47.4%])符合进行分析的条件。中位随访时间为9.0年。与戒酒者相比,饮酒<5 d/wk的人群(I和III类饮酒者)发生缺血性卒中的风险明显更低(I类饮酒者风险比为0.71 [95%CI为0.59-0.85];III类饮酒者风险比为0.80 [95%CI为0.68–0.93]),而其他饮酒者组则无此差异。但是,饮酒方式对缺血性卒中风险的影响在7年后有所减弱。

由此可见,在特定饮酒方式的中年参与者中,缺血性卒中的风险降低,但仅限于早期。考虑到饮酒方式与缺血性卒中之间的长期联系,医师在对患者饮酒的教育方面应保持谨慎。

原始出处:

Wookjin Yang,et al.Drinking Patterns and Risk of Ischemic Stroke in Middle-Aged Adults Do Beneficial Drinking Habits Indeed Exist?.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032144

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    2020-12-15 1dedaedcm53(暂无匿称)

    少量饮酒有益?

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1946119, encodeId=01a2194611997, content=<a href='/topic/show?id=a244101210d5' target=_blank style='color:#2F92EE;'>#饮酒方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101210, encryptionId=a244101210d5, topicName=饮酒方式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Mon Apr 05 00:48:30 CST 2021, time=2021-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806407, encodeId=70e1180640e56, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Thu Jun 17 14:48:30 CST 2021, time=2021-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=908365, encodeId=174890836507, content=少量饮酒有益?, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c201726730, createdName=1dedaedcm53(暂无匿称), createdTime=Tue Dec 15 23:03:04 CST 2020, time=2020-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893334, encodeId=4216189333439, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Mar 18 10:48:30 CST 2021, time=2021-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281351, encodeId=8bac1281351b6, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Nov 09 00:48:30 CST 2020, time=2020-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026710, encodeId=4b071026e10d8, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Nov 07 12:48:30 CST 2020, time=2020-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1045989, encodeId=a51d1045989fe, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Sat Nov 07 12:48:30 CST 2020, time=2020-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=897518, encodeId=106689e518dc, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201107/0fd6d468b9b547f2b6d8d9ba206d67d4/a59c3b4eed764cdaa3d99bd257d8c034.jpg, createdBy=3edc5432547, createdName=Scrophu, createdTime=Sat Nov 07 09:56:33 CST 2020, time=2020-11-07, status=1, ipAttribution=)]
    2020-11-07 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2020-11-07 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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    2020-11-07 Scrophu

    学习了

    0

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Stroke:胃肠道疾病与首次缺血性卒中风险之间的关系

在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。

Stroke:高血糖与缺血性卒中患者血管内治疗后不良结局相关

入院血糖升高与功能不良和血管内治疗后症状性颅内出血风险增加有关。

Stroke:抗磷脂抗体与缺血性卒中风险

aPL并不是成人RIS的独立预测因子。但是,考虑到非标准化的疾病标准,应考虑进一步设计良好的前瞻性试验以证实这些结果。

Circulation:将LDL-C浓度控制在70 mg/dL以下或以上对颈动脉粥样硬化斑块发生的影响

TST试验显示,在2860例伴有脑血管粥样硬化性狭窄的缺血性卒中患者中,将低密度脂蛋白胆固醇浓度控制在70 mg/dL以下可降低主要心血管事件风险。但该策略对颈动脉粥样硬化演变的影响尚不明确

J INTERN MED:痴呆患者服用钙通道阻滞剂与生存率和缺血性卒中之间的关系

对于AD和DLB-PDD的痴呆患者服用氨氯地平可降低死亡风险。与其他CCB使用者相比,使用氨氯地平的AD患者发生缺血性卒中的风险较低。