Stroke:大血管闭塞性卒中患者白质高信号负担与侧支循环

2021-09-16 MedSci原创 MedSci原创

白质高信号(WMH)是一种慢性脑小血管疾病的标志,WMH负担与大血管闭塞性卒中患者侧支循环之间没有明显关联。

白质高信号(WMH)是一种慢性脑小血管疾病的标志,可能会影响软脑膜侧支循环的形成。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估WMH负担是否与接受血管内血栓切除术治疗前循环急性缺血性卒中患者侧支循环之间的相关性。


研究人员纳入2015年1月至2017年12月因前循环大血管闭塞并接受血管内取栓治疗的连续就诊的急性缺血性卒中患者,并通过流体衰减反转恢复-磁共振成像的半自动体积分析对WMH体积(脑室周围、深部和总体积)进行评估。研究人员使用美国介入和治疗神经放射学会/介入放射学会分级系统(≥3时为好)在基线导管血管造影术中对侧支状态进行分级。研究人员调查了WMH负担与侧支状态之间的关联。

该研究总共纳入了302名患者(平均年龄为69.1±19.4岁;女性占55.6%)。研究人员在49.3%的患者中观察到了不良的侧支循环。WMH总体积中位数为3.76 cm3(四分位距为1.09-11.81cm3)。回归分析显示WMH负担与基线血管造影评估的侧支状态之间没有明显关系(调整后的比值比为0.987[95%CI为0.971-1.003];P=0.12)。
 
由此可见,WMH负担与大血管闭塞性卒中患者侧支循环之间没有明显关联。

原始出处:

Imad Derraz.et al.White Matter Hyperintensity Burden and Collateral Circulation in Large Vessel Occlusion Stroke.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.031736

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    2021-11-09 kkunny
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encodeId=7916141e5843e, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052109, encodeId=190010521092a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58c55294961, createdName=1487042cm12暂无昵称, createdTime=Thu Sep 16 21:59:25 CST 2021, time=2021-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052605, encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1950838, encodeId=a201195083809, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Mon Feb 21 17:23:42 CST 2022, time=2022-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706185, encodeId=90481e061850f, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, 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objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Thu Aug 25 19:23:42 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390668, encodeId=faf113906684b, content=<a href='/topic/show?id=796e26955ce' target=_blank style='color:#2F92EE;'>#侧支循环#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26955, encryptionId=796e26955ce, topicName=侧支循环)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417584, encodeId=7916141e5843e, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052109, encodeId=190010521092a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58c55294961, createdName=1487042cm12暂无昵称, createdTime=Thu Sep 16 21:59:25 CST 2021, time=2021-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052605, encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1950838, encodeId=a201195083809, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Mon Feb 21 17:23:42 CST 2022, time=2022-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706185, encodeId=90481e061850f, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, 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objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Thu Aug 25 19:23:42 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390668, encodeId=faf113906684b, content=<a href='/topic/show?id=796e26955ce' target=_blank style='color:#2F92EE;'>#侧支循环#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26955, encryptionId=796e26955ce, topicName=侧支循环)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417584, encodeId=7916141e5843e, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052109, encodeId=190010521092a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58c55294961, createdName=1487042cm12暂无昵称, createdTime=Thu Sep 16 21:59:25 CST 2021, time=2021-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052605, encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1950838, encodeId=a201195083809, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Mon Feb 21 17:23:42 CST 2022, time=2022-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706185, encodeId=90481e061850f, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, 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objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Thu Aug 25 19:23:42 CST 2022, time=2022-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390668, encodeId=faf113906684b, content=<a href='/topic/show?id=796e26955ce' target=_blank style='color:#2F92EE;'>#侧支循环#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26955, encryptionId=796e26955ce, topicName=侧支循环)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417584, encodeId=7916141e5843e, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Sat Sep 18 04:23:42 CST 2021, time=2021-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052109, encodeId=190010521092a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58c55294961, createdName=1487042cm12暂无昵称, createdTime=Thu Sep 16 21:59:25 CST 2021, time=2021-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052605, encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1950838, encodeId=a201195083809, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Mon Feb 21 17:23:42 CST 2022, time=2022-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706185, encodeId=90481e061850f, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
    2021-09-16 1487042cm12暂无昵称

    学习

    0

  10. 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encodeId=a13d10526056f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Sep 16 16:23:42 CST 2021, time=2021-09-16, status=1, ipAttribution=)]
    2021-09-16 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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