Stroke:中脑周围出血的流行病学、危险因素、可能病因、临床病程及结局分析!

2018-04-25 xing.T MedSci原创

由此可见,单次、高分辨率的CT血管造影是中脑周围出血首选的诊断策略。短期并发症较为罕见,并且往往是短暂的。对于残疾和死亡的长期结局较好,但需要专注于神经心理学后遗症的高质量研究进行证实。

近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员系统地回顾了有中脑周围出血的流行病学、危险因素、可能病因、临床病程和预后的文献。

研究人员检索了PubMed、EMABASE和Cochrane图书馆等数据库,检索时间截止至2016年3月。文献的质量评价由2位作者独立完成。研究人员采用从病例对照研究中提取的数据计算了合并的患病率比和比值比以及95%可信区间。

该分析共纳入了208篇论文,中脑周围出血的发生率为每10000人每年约0.5例,男性受影响较多,无明确的危险因素。两个决策分析都发现单次、高分辨率的计算机断层血管造影是首选的诊断方法。短期并发症,如脑积水或颅神经麻痹,较为是罕见,通常是短暂的,除了3%的需要治疗的急性症状性脑积水患者。仅4例患者证实为脑干腔隙性梗死。1例患者在抗凝治疗后出血初期出现致命性再出血。在长期随访中,未发现与出血相关的死亡,发生残疾的比例为0%~6%,提示存在神经心理后遗症。

由此可见,单次、高分辨率的CT血管造影是中脑周围出血首选的诊断策略。短期并发症较为罕见,并且往往是短暂的。对于残疾和死亡的长期结局较好,但需要专注于神经心理学后遗症的高质量研究进行证实。

原始出处:

Liselore A. Mensing,et al. Perimesencephalic Hemorrhage A Review of Epidemiology, Risk Factors, Presumed Cause, Clinical Course, and Outcome.Stroke. 2018. https://doi.org/10.1161/STROKEAHA.117.019843

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    2018-04-27 xugumin
  4. [GetPortalCommentsPageByObjectIdResponse(id=1797102, encodeId=57f61e9710203, content=<a href='/topic/show?id=6b2322411e1' target=_blank style='color:#2F92EE;'>#中脑周围出血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22411, encryptionId=6b2322411e1, topicName=中脑周围出血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Sun Jun 03 07:38:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077247, encodeId=5bbf20e72470d, content=<a href='/topic/show?id=972022912f1' target=_blank style='color:#2F92EE;'>#临床病程#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22912, encryptionId=972022912f1, topicName=临床病程)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/BF4BC9769C2FF12AC93CAA0069C0696C/100, createdBy=7bb22500091, createdName=ms1292405679162969, createdTime=Thu Oct 04 06:38:00 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411299, encodeId=7ecf14112990b, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Apr 27 09:38:00 CST 2018, time=2018-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309198, encodeId=ec2e3091981d, content=不错.学习了.做笔记了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Apr 25 18:44:20 CST 2018, time=2018-04-25, status=1, ipAttribution=)]
    2018-04-25 虈亣靌

    不错.学习了.做笔记了.谢谢分享!

    0