淋巴结转移可预测无浆膜浸润胃癌患者预后

2012-06-23 小哲 摘编 医学论坛网

  近日,大连医科大学附属第一医院普通外科胡祥、曹亮、于艺等人共同发表论文,旨在探讨淋巴结转移对无浆膜浸润胃癌预后的影响。研究指出,无论是按转移淋巴结的范围还是数量进行评价,淋巴结转移均能对无浆膜浸润胃癌患者的预后作出较好的预测。该文发表在2012 年第15卷第2期《中华胃肠外科杂志》上。   回顾性分析1994年1月至2005年12月间大连医科大学附属第一医院普通外科行D2或D2以上

  近日,大连医科大学附属第一医院普通外科胡祥、曹亮、于艺等人共同发表论文,旨在探讨淋巴结转移对无浆膜浸润胃癌预后的影响。研究指出,无论是按转移淋巴结的范围还是数量进行评价,淋巴结转移均能对无浆膜浸润胃癌患者的预后作出较好的预测。该文发表在2012 年第15卷第2期《中华胃肠外科杂志》上。

  回顾性分析1994年1月至2005年12月间大连医科大学附属第一医院普通外科行D2或D2以上胃癌根治术、且具有完整随访资料的616例无浆膜浸润胃癌患者的临床资料;并选取同期接受相同术式的有浆膜浸润的162例胃癌患者为对照组。

  无浆膜浸润胃癌患者的5年生存率为77.9%,明显高于浆膜浸润组的37.3%。不同浸润深度患者5年生存率分别为T1a(M)95.6%,T1b(SM)92.5%,T2(MP)73.5%,T3(SS)62.7%,T4(SE、SI)37.3%。按日本第13版《胃癌处理规约》,N0、N1(第1站)、N2(第2站)和N3(第3站)无浆膜浸润胃癌患者的5年生存率分别为91.5%、75.3%、54.8%和14.7%,差异有统计学意义;按第7版TNM分期,N0、N1(1~2枚)、N2(3~6枚)、N3a(7~15枚)和N3b(15枚以上)无浆膜浸润胃癌患者的5年生存率分别为91.5%、83.6%、59.8%、17.2%和11.8%,差异亦有统计学意义。淋巴结转移是无浆膜浸润胃癌患者预后的独立预后因素。
    

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    2012-06-25 sodoo
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