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ASJ：血小板源性高浓度生长因子对单层、多层及压碎复合软骨移植的影响

2021-04-23 MedSci原创 MedSci原创

软骨移植血小板源性高浓度生长因子
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自体软骨移植广泛应用于当前的整形手术中。软骨移植物常被用于耳鼻的美容和重建手术，但也被用于其他许多区域的增厚和和重建，如乳头重建、颅骨成形术和爆裂性骨折。

自体软骨移植广泛应用于当前的整形手术中。软骨移植物常被用于耳鼻的美容和重建手术，但也被用于其他许多区域的增厚和和重建，如乳头重建、颅骨成形术和爆裂性骨折。 利用软骨移植物来实现结构完整性和体积恢复的主要问题是随着时间的推移体积的损失及其不可预测的生存能力。保存软骨移植物的体积是保证其长期成功的必要条件。 本研究的主要目的是探讨血小板源性高浓度生长因子（CGF）片对单层、多层及压碎块状软骨移植物的影响。 从兔耳获得的软骨移植物以3种不同形式制备：单层、三层和压碎。实验组在测量移植软骨的重量和厚度后，用制备的自体CGF包裹移植软骨。这些软骨移植物被放置在兔子背部的皮下袋中。4个月后处死家兔。 图1CGF的制备 (A）去除血浆血小板层 (B）去除红细胞层后，将CGF压缩 (C）最终的CGF层包裹软骨移植物。 图2从耳廓软骨上取上排软骨移植物，以5cm的间隔移植在距中线4cm的位置 测量软骨移植物的重量和厚度，显微镜下观察软骨活力和周围变化。 单层、多层和压碎的软骨移植物用CGF包裹后，其重量和厚度的百分比变化在统计学上显著低于对照组。 表1.不同类型软骨移植物植入前后厚度变化的比较 &nbs

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    2021-07-08 howi

    #骨移植#

    0

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    2021-04-25 12499e01m50暂无昵称

    #生长因子#

    0

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    2021-04-25 12498974m55暂无昵称

    #浓度#

    0

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    2021-04-23 12d73e06m63暂无昵称

    学习前沿知识

    0

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