JACC:药物涂层球囊扩张和药物涂层支架植入对冠脉再狭窄患者的比较研究

2020-05-31 MedSci原创 MedSci原创

本研究旨在比较和评价药物涂层球囊血管成形术(DCB)和重复支架置入药物涂层支架(DES)治疗裸金属支架(BMS)或药物涂层支架(DES)冠脉支架内再狭窄(ISR)患者的疗效和安全性。

本研究旨在比较和评价药物涂层球囊血管成形术(DCB)和重复支架置入药物涂层支架(DES)治疗裸金属支架(BMS)或药物涂层支架(DES)冠脉支架内再狭窄(ISR)患者的疗效和安全性。

本研究纳入分析了DAEDALUS临床研究中的710名BMS-ISR患者和1248名DES-ISR患者,主要疗效终点是3年后靶点病变血管重建(TLR)。主要安全终点是3年内的全因死亡、心肌梗死或靶病变血栓形成。在BMS-ISR患者中,两种治疗方法对主要疗效终点和安全终点的影响无明显差异。在DES-ISR患者中,DCB血管成形术的主要疗效终点风险高于DES重复植入术,而主要安全终点的风险更低。另外,无论采用何种治疗,BMS比DES-ISR的TLR风险都更低。

研究结果显示,对于裸金属支架植入后支架内再狭窄患者,药物涂层球囊血管成形术和重复支架置入药物涂层支架在有效性和安全性方面无明显差异,对于药物涂层支架植入后支架内再狭窄患者,药物涂层球囊血管成形术的有效性要差于重复支架置入药物涂层支架。

原始出处:

Daniele G et al.Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent Implantation in Patients With Coronary Stent Restenosis.JACC.2020 May.

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channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68635, encryptionId=2e956863556, topicName=球囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0361487, createdName=花花1366, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1486213, encodeId=bab21486213ab, content=<a href='/topic/show?id=15b93065283' target=_blank style='color:#2F92EE;'>#再狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30652, encryptionId=15b93065283, topicName=再狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bf8f8090913, createdName=12498f1em10(暂无昵称), createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520680, encodeId=8b13152068084, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559910, encodeId=4c501559910f1, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565919, encodeId=9fba156591945, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=)]
    2020-06-15 lsj637
  5. [GetPortalCommentsPageByObjectIdResponse(id=1854789, encodeId=b9081854e8979, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jan 14 08:23:12 CST 2021, time=2021-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688441, encodeId=95b61688441f9, content=<a href='/topic/show?id=360f686434a' target=_blank style='color:#2F92EE;'>#球囊扩张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68643, encryptionId=360f686434a, topicName=球囊扩张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=401d28589001, 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time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565919, encodeId=9fba156591945, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1854789, encodeId=b9081854e8979, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jan 14 08:23:12 CST 2021, time=2021-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688441, encodeId=95b61688441f9, content=<a href='/topic/show?id=360f686434a' target=_blank style='color:#2F92EE;'>#球囊扩张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68643, encryptionId=360f686434a, topicName=球囊扩张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=401d28589001, 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time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565919, encodeId=9fba156591945, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=)]
    2020-06-02 花花1366
  7. 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time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565919, encodeId=9fba156591945, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=)]
  8. 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time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565919, encodeId=9fba156591945, content=<a href='/topic/show?id=020e8e802a9' target=_blank style='color:#2F92EE;'>#药物涂层球囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87802, encryptionId=020e8e802a9, topicName=药物涂层球囊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=597715042971, createdName=circumcision, createdTime=Tue Jun 02 12:23:12 CST 2020, time=2020-06-02, status=1, ipAttribution=)]
    2020-06-02 jiyangfei
  9. 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1. 心血管风险与认知功能下降的相关性研究

JAHA:体育锻炼和空气污染对心血管风险的组合影响

体力活动(PA),特别是户外PA,可能对心血管疾病(CVD)风险有双重影响:运动对健康的益处和因暴露于空气污染而产生的潜在有害影响。本研究的目的旨在评估PA和空气污染对心血管疾病风险的组合影响。

冠状病毒与心血管系统:短期和长期影响

近期,《European Heart Journal》刊登了一篇文章,聚焦冠状病毒对心血管系统的短期和长期影响,除Covid-19外,文章同时回顾了SARS和MERS的心血管影响。