Stroke:高度颈动脉狭窄的种族差异

2021-05-05 MedSci原创 MedSci原创

尽管他们不良心血管危险因素更多,但黑人和西班牙裔高度颈动脉狭窄患病率相对于白人要低。

尽管与白人相比,黑人和西班牙裔卒中的发生率更高,不良血管危险因素更多,但在这些人群中,颈动脉血运重建的频率较低。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员评估了高度(直径缩小≥70%)颈动脉狭窄的种族差异。

在这项横断面研究中,研究人员评估了2005年至2019年期间全国生命线专营服务以筛查血管疾病患者,并通过颈动脉超声测得的峰值收缩期速度≥230cm/s来确定高度颈动脉狭窄的患病率。受试者自我报告为白人、黑人、西班牙裔、亚洲人、美洲原住民或其他人。研究人员使用Poisson回归评估人种/种族差异。

高度颈动脉狭窄的患病率估计有6130481人。在所有种族性别分层中,高度颈动脉狭窄的患病率随着年龄的增长而增加。通常,与白人相比,黑人和西班牙裔人的高度颈动脉狭窄患病率较低,而美洲原住民的患病率较高。

例如,对于55至65岁的男性,黑人和西班牙裔美国人相对于白人的颈动脉狭窄相对风险分别为0.40(95%CI为0.29-0.55)和0.61(95%CI为0.46-0.81);而美洲原住民为1.53(95%CI为1.12–2.10)。当这一患病率估计值应用于美国人口普查时,估计有327721人患有高度颈动脉狭窄,其中7%是黑人,7%是西班牙裔,而43%是女性。

尽管他们不良心血管危险因素更多,但黑人和西班牙裔高度颈动脉狭窄患病率相对于白人要低。高度颈动脉狭窄的患病率较低可能是导致这些少数人群颈动脉血运重建使用率较低的潜在原因。

原始出处:

Brajesh K. Lal.et al.Race Differences in High-Grade Carotid Artery Stenosis.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032723

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    2021-05-05 1324dc70m03暂无昵称

    常规筛查

    0

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    2021-05-05 jyzxjiangqin

    好文章!

    0

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