Stroke:卒中前行动不便患者血管内治疗的结局

2021-09-14 MedSci原创 MedSci原创

尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。

卒中前行动不便(PSMI)患者被排除在血管内临床试验之外。关于这类人群血管内血栓切除术的安全性和结局的数据十分有限。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员使用了一个大型的国家数据集来评估PSMI患者血管内血栓切除术的安全性和结局。

 
研究人员纳入了2015年至2019年期间接受血管内血栓切除术的患者。PSMI被定义为无法独立行走。研究人员采用Logistic回归模型的广义估计方程评估PSMI与结局之间的关联。

在接受血管内血栓切除术治疗的56762名患者中,2919名(5.14%)为PSMI患者。PSMI与有症状的颅内出血无关(6.0% vs. 5.4%;P=0.979)。32.3%的PSMI患者发生院内死亡或出院到临终关怀医院,而非PSMI患者为17.5%(调整后的比值比为1.45[1.32–1.58])。
 
由此可见,尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。

原始出处:

Rachel Beekman.et al.Outcomes of Endovascular Therapy in Patients With Prestroke Mobility Impairment.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.034464

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1057403, encodeId=9761105e403a6, content=<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:06:54 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051435, encodeId=d5741051435e9, content=非常有意思的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9771664520, createdName=tony要要要, createdTime=Wed Sep 15 10:40:35 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051326, encodeId=9009105132693, content=关注失能人群的人生终末治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Sep 14 23:37:51 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052604, encodeId=ac6d105260455, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 14 22:44:28 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051302, encodeId=421c105130225, content=谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdb5535422, createdName=ms5000001978187696, createdTime=Tue Sep 14 22:40:46 CST 2021, time=2021-09-14, status=1, ipAttribution=)]
    2021-10-04 1def6e10m76(暂无匿称)

    #卒中#尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1057403, encodeId=9761105e403a6, content=<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:06:54 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051435, encodeId=d5741051435e9, content=非常有意思的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9771664520, createdName=tony要要要, createdTime=Wed Sep 15 10:40:35 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051326, encodeId=9009105132693, content=关注失能人群的人生终末治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Sep 14 23:37:51 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052604, encodeId=ac6d105260455, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 14 22:44:28 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051302, encodeId=421c105130225, content=谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdb5535422, createdName=ms5000001978187696, createdTime=Tue Sep 14 22:40:46 CST 2021, time=2021-09-14, status=1, ipAttribution=)]
    2021-09-15 tony要要要

    非常有意思的研究

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1057403, encodeId=9761105e403a6, content=<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:06:54 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051435, encodeId=d5741051435e9, content=非常有意思的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9771664520, createdName=tony要要要, createdTime=Wed Sep 15 10:40:35 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051326, encodeId=9009105132693, content=关注失能人群的人生终末治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Sep 14 23:37:51 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052604, encodeId=ac6d105260455, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 14 22:44:28 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051302, encodeId=421c105130225, content=谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdb5535422, createdName=ms5000001978187696, createdTime=Tue Sep 14 22:40:46 CST 2021, time=2021-09-14, status=1, ipAttribution=)]
    2021-09-14 452946589

    关注失能人群的人生终末治疗

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1057403, encodeId=9761105e403a6, content=<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:06:54 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051435, encodeId=d5741051435e9, content=非常有意思的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9771664520, createdName=tony要要要, createdTime=Wed Sep 15 10:40:35 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051326, encodeId=9009105132693, content=关注失能人群的人生终末治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Sep 14 23:37:51 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052604, encodeId=ac6d105260455, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 14 22:44:28 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051302, encodeId=421c105130225, content=谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdb5535422, createdName=ms5000001978187696, createdTime=Tue Sep 14 22:40:46 CST 2021, time=2021-09-14, status=1, ipAttribution=)]
    2021-09-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1057403, encodeId=9761105e403a6, content=<a href='/topic/show?id=b64035999ca' target=_blank style='color:#2F92EE;'>#卒中#</a>尽管PSMI患者的手术不良结局发生率并没有升高,但需要进一步研究以确定该人群的临床获益。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35999, encryptionId=b64035999ca, topicName=卒中)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTInOuicIVN8Y32NO4Q53Zpd86ObmNp2WIotichCD0qQHaUBeHj7hgwQBCzX7ce4aEw5ZP8icQQfLH9Zw/132, createdBy=4ec21734756, createdName=1def6e10m76(暂无匿称), createdTime=Mon Oct 04 09:06:54 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051435, encodeId=d5741051435e9, content=非常有意思的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9771664520, createdName=tony要要要, createdTime=Wed Sep 15 10:40:35 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051326, encodeId=9009105132693, content=关注失能人群的人生终末治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Sep 14 23:37:51 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052604, encodeId=ac6d105260455, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 14 22:44:28 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051302, encodeId=421c105130225, content=谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdb5535422, createdName=ms5000001978187696, createdTime=Tue Sep 14 22:40:46 CST 2021, time=2021-09-14, status=1, ipAttribution=)]
    2021-09-14 ms5000001978187696

    谢谢了

    0

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