Med Sci Sports Exerc:客观测量的体力活动与膝关节骨性关节炎的发生风险

2018-04-10 张玮扬 北体大运动处方研究中心

膝关节骨性关节炎(OA)会限制膝关节的功能及活动,影响生活质量,是膝关节置换术后的主要并发症且与大量的医疗支出相关。体力活动会增加膝关节压力,但体力活动强度与OA发生风险的增加之间的关系是不清楚的。

研究背景:

膝关节骨性关节炎(OA)会限制膝关节的功能及活动,影响生活质量,是膝关节置换术后的主要并发症且与大量的医疗支出相关。体力活动会增加膝关节压力,但体力活动强度与OA发生风险的增加之间的关系是不清楚的。

研究目的:

旨在探讨客观测量的中等强度体力活动(MVPA)与发生膝关节骨性关节炎(OA)的风险之间的关系,研究以社区中老年人队列为基础。

研究方法:

我们使用的数据来自一项有关骨关节炎的前瞻性队列研究,研究对象为45-83岁成人。使用单轴加速度计对中等强度体力活动(MVPA)进行2次连续7天的数据采集,分为体力活动不活跃(<10分/周)、低水平体力活动(10-<150分/周)及体力活动活跃(≥150分/周)。对受试者影像学、OA症状、膝关节间隙狭窄的4年随访。基线时受试者双膝无OA,我们用95%置信区间来确定风险比。

研究结果:

在多变量分析中,与受试者不活跃的及低体力活动MVPA相比,活跃的MVPA与影像学OA风险(HR=1.52,95%CI=0.68-3.40)、有症状的OA(HR=1.17,95%CI=0.44-3.09)、膝关节间隙狭窄(HR=0.87,95%CI=0.37-2.06)风险都没有显著相关性。

研究结论:

在4年随访中,MVPA与OA事件或膝关节间隙狭窄的发生风险没有相关性。

原始出处:
QIN, J., et al. Objectively Measured Physical Activity and Risk of Knee Osteoarthritis. Medicine & Science in Sports & Exercise: February 2018 - Volume 50 - Issue 2 - p 277–283.

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    2018-04-12 lmm397
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    2018-04-10 清风拂面

    谢谢分享学习

    0

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