JACC:经股路径和非经股路径TAVR的比较研究

2019-11-26 不详 MedSci原创

股动静脉路径是经导管主动脉瓣置换术(TAVR)的金标准路径,指南中推荐不能经股路径的患者转为外科手术治疗,然而,其它外周路径可作为替代方案。本研究的目的旨在评估和比较非股路径TAVR和经股路径TAVR的异同。本研究回顾分析了法国FRANCE TAVI数据库中的21611名接受TAVR的病人,其中92.5%的患者为经股路径,7.5%的患者接受的是非经股路径TAVR(914名为经颈动脉路径,702名为

股动静脉路径是经导管主动脉瓣置换术(TAVR)的金标准路径,指南中推荐不能经股路径的患者转为外科手术治疗,然而,其它外周路径可作为替代方案。本研究的目的旨在评估和比较非股路径TAVR和经股路径TAVR的异同。

本研究回顾分析了法国FRANCE TAVI数据库中的21611名接受TAVR的病人,其中92.5%的患者为经股路径,7.5%的患者接受的是非经股路径TAVR(914名为经颈动脉路径,702名为锁骨下静脉路径)。与经股路径患者相比,非经股路径患者的严重疾病发生风险更高、外周血管疾病、冠心病、慢性肺病和肾功能不全的发生风险更高。经过倾向性匹配后,两组患者在术后死亡率和并发症发生率方面无明显差异,但非经股路径患者的主要血管并发症和血管损伤的发生率更低。

研究结果显示,非经股路径的TAVR患者预后和经股路径无明显差异,并且主要血管并发症和血管损伤的发生率更低。因此,对于不能经股路径的患者,经其它外周路径可能优于外科手术治疗。


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    2021-03-23 病毒猎手
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    2020-09-24 hbwxf
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