JAHA:年龄对收缩压与心血管病风险相关性的影响研究

2020-07-18 MedSci原创 MedSci原创

糖尿病患者收缩压(SBP)与心血管疾病(CVD)的关系尚不清楚。本研究旨在探讨SBP与CVD之间的年龄相关性。

糖尿病患者收缩压(SBP)与血管疾病(CVD)的关系尚不清楚。本研究旨在探讨SBP与CVD之间的年龄相关性。

本研究纳入分析了180492名中国2型糖尿病成年患者,经过平均9.3年时间的随访,32545名患者发展为CVD,发病率为23.4/1000人年。在4个年龄组(<50、50-59、60-69和70-79岁)中,观察到SBP和CVD风险之间存在正相关和对数线性关系,但SBP对CVD的影响随年龄增长而减弱。年龄<50岁患者的CVD风险要比70-79岁患者高22%。每升高10毫米汞柱SBP,分别与12%(HR,1.12[95%CI,1.10-1.13])、11%(HR,1.11[95%CI,1.10-1.13])和20%(HR,1.20[95%CI,1.17-1.22])的所有复合心血管疾病事件、个体心血管疾病和心血管疾病死亡率的风险增加相关。

研究结果显示,对于糖尿病患者,收缩压与心血管病风险呈明显线性相关,年龄对这一关系有明显影响,与年龄较大的患者相比,年轻患者(<50岁)对这种相关性影响更大。

原始出处:

Eric Y et al.Age‐Specific Associations Between Systolic Blood Pressure and Cardiovascular Disease: A 10‐Year Diabetes Mellitus Cohort Study.JAHA.2020 July.

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    2020-07-20 zhaohui6731
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    2020-07-19 yangchou

    很实用的研究

    0

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    2020-07-18 lovetcm

    #心血管病#研究越来越细致

    0

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