眼眶骨折中如何评估严重眼外伤风险?看看这些指标!--JAMA Ophthalmology

2020-11-30 MedSci原创 MedSci原创

与眼损伤风险增加相关的5个变量是:异物挫伤、无法计数手指、眼顶骨折、初次凝视时复视、结膜出血或化瘀。

据估计,10%至25%出现在急诊科的面部创伤涉及眼眶骨折。幸运的是,在眼骨折的情况下,总的眼外伤的发生率很低,73%到92.3%的眼眶骨折患者没有相关的眼外伤。此外,大部分眼骨折的眼部表现是良性的(例如,结膜下出血或眼眶周围肿胀),并且这种损伤不需要眼科手术干预,也不会导致长期的眼部后遗症。然而,非眼科医生通常没有足够的材料和经验来做扩眼检查来确定是否有实质性的眼部损伤,急诊或面部整形医生很难对所有病例进行有经验的眼科评估。,因此有必要开发预测工具来评估并发眼外伤的风险。为了确定在眼眶骨折的情况下,哪些临床和影像学特征与实质性眼外伤风险的增加有关,一篇研究对此进行了探讨,结果发表在JAMA Ophthalmology杂志上。

本研究为回顾性病例系列研究:2012年至2018年间眼眶骨折患者的回顾性连续病例系列。在急诊或住院的2个1级创伤中心中的1个进行检查。2012年至2017年间,共有430名连续患者(500只眼)符合培训样本的纳入标准。在建立预测模型后,在2017年至2018年间,又收集了88名符合纳入标准的连续患者(97只眼)作为测试样本。主要观察指标是明显不同于眼眶骨折的实质性眼外伤。

大多数咨询(83.9%;370名患者)直接来自急诊科,近一半的眼眶骨折来自跌倒患者(52.6%;226名患者)。共有80例患者(18.8%)处于昏昏欲睡或插管状态。年龄52.9(21.3)岁。最常见的骨折类型是内部骨折(眼眶底和/或内侧壁,共45.8%或229只眼),最常见的检查结果是眼睑瘀斑(65.4%;327眼)和结膜下出血(61%;304只眼睛)。

眼眶骨折时发生明显眼外伤的频率

结果显示,患者的平均年龄为53.5岁(16-100岁)。严重眼外伤的总发生率为20.4%,需要立即眼科治疗的受伤率为14.4%。五个变量被发现与实质性眼外伤的风险增加相关:异物钝性外伤(优势比[OR],19.4;95%CI,6.3-64.1;P<0.001),无法计数手指(OR,10.1;95%CI,2.8-41.1;P=0.002),顶骨骨折(OR,9.1;95%CI,2.8-30.0;P=0.002),初级注视复视(OR,6.7;95%CI,1.7-25.1;P=0.003),结膜出血或化脓(or,4.2;95%CI,2.2-8.5;P<0.001)。

这些发现可以帮助非眼科医生对眼眶骨折的患者进行紧急眼科评估。对于非眼科医生来说,如果没有适当的光学矫正和/或针孔咬合器以及良好的患者配合来获得如此精确的视力通常是不可行的。此外,在外伤的情况下,眼眶可能会肿胀、闭合,并且会出现严重的眼周和眼眶周围疼痛,这进一步妨碍了对视力的精确测量。研究者发现这对任何实际算法都是至关重要的,因为这项研究中有近20%的咨询患者是插管或昏睡。由于这些变化,该算法在床边设置工作良好,对于非眼科医生来说它会成为一个有用的分类工具。

总之,在这篇研究中,研究者描述了一种评估面部创伤和眼眶骨折患者实质性眼外伤的临床算法。与眼损伤风险增加相关的5个变量是:异物挫伤、无法计数手指、眼顶骨折、初次凝视时复视、结膜出血或化瘀。这些变量与高敏感性(95.4%)和高阴性预测值(96.8%)的实质性眼外伤风险增加有关,同时也与较低的特异性(40%)和阳性预测值(31.8%)相平衡。这些发现如果在独立的前瞻性纵向调查中得到证实,将支持对那些基于床旁评估的面部创伤和眼眶骨折的严重眼外伤高危患者的评估。

参考文献:Rossin, E. J., Szypko, C., Giese, I., Hall, N., Gardiner, M. F., & Lorch, A. (2020). Factors Associated With Increased Risk of Serious Ocular Injury in the Setting of Orbital Fracture. JAMA Ophthalmology. doi:10.1001/jamaophthalmol.2020.5108 

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    2021-09-15 SASORIxxxx

    希望多发这样的研究文章!

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    2021-04-12 122a5e7dm85暂无昵称

    学习了

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    2021-03-17 330911029

    学习了

    0

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    2020-11-30 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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    2020-11-30 381117495

    学习了

    0