Mol Psychiatr:患有多囊卵巢综合征(PCOS)女性可能会导致后代患自闭症的几率增高!

2015-12-09 chenshuo 译 MedSci原创

近日,瑞典卡罗林斯卡学院公共卫生科学系Kyriaki Kosidou博士在分子精神病学杂志上发表了一项最新的研究成果,研究成果首次发现母亲患有多囊卵巢综合征,可能导致日后子女患上自闭症的风险水平增高。

近日,瑞典卡罗林斯卡学院公共卫生科学系Kyriaki Kosidou博士在分子精神病学杂志上发表了一项最新的研究成果,研究成果首次发现母亲患有多囊卵巢综合征,可能导致日后子女患上自闭症的风险水平增高。


图片来自MedicalNewsToday.com

自闭症---一种发育障碍,其特征是社会、交流和行为出现障碍。目前在美国平均每68名儿童就有1名儿童患有自闭症。

对于自闭症的确切原因目前尚不清楚,据以往的研究表明,儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素。

通常情况下,不管是男性还是女性,他们体内产生所产生的雄激素(如睾酮和雄烯二酮)一般会被称为“男性荷尔蒙,因为雄激素的主要生理作用就是维持男性特征,而雄激素一般只会在男性体内分泌较多。研究表明,雄激素有助于人体大脑的发育。

以往的研究表明,患有多囊卵巢综合征(PCOS)的女性雄激素的分泌量会有多增加,而雄激素的含量过高反而又会影响卵巢的功能。

因此,Kyriaki Kosidou 博士认为,患有多囊卵巢综合征(PCOS)的女性在怀孕期间可能会影响后代自闭症的发病几率。

为了证实他的猜测,Kyriaki Kosidou 博士带领他的研究团队进行了一系列的研究。研究小组调查了瑞典卫生和人口登记数据库收集到的所有儿童年龄在4-17岁(1984-2007年期间)的个人信息。

最后,研究人员确定了24000名患有自闭症的儿童作为试验组,200000名非自闭症儿童作为对照组。

研究结果发现,与那些母亲没有患有PCOS出生的孩子相比,那些患病PCOS的母亲的孩子在出生后发生自闭症的几率高出了59%。

研究团队认为,这可能是由于患有PCOS的母亲在怀孕期间体内的雄激素水平过高导致的结果。

虽然目前社会上出现自闭症的儿童越来越多,且男孩比女孩相对较多,但研究团队发现,在那些患有PCOS的母亲所生的孩子(患有自闭症)中男女比例是一样的。

直到如今,研究小组成员尚无法确定为何患有PCOS的女性的孩子出现自闭症的的确切原因,但他们推测母亲患有PCOS和后代自闭症风险水平增加之间的关联可能是通过雄激素水平增高驱动的。另外,它也有可能是自闭症和多囊卵巢综合征有共同的遗传因素。

最后,研究小组成员说,目前尚且需要进一步的研究来证实他们的发现,并确定潜在的机制原理。

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    2018-10-22 Susanheee

    儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素

    0

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15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45461, encodeId=5a68454619d, content=高雄, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 10 14:16:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2016-02-16 mengli1984

    和激素水平有关?

    0

  4. 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15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, 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    2016-01-28 1de3b290m83(暂无匿称)

    有干预措施吗

    0

  5. 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15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, 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    2016-01-20 ssummer

    感谢分享

    0

  6. 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authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45461, encodeId=5a68454619d, content=高雄, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 10 14:16:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=350141, encodeId=1f3a35014173, content=儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZib5pXwccy19pABmFn91nGEwyWbA7qibiaOHVwhzltCSm8rkUSTM3QNkuj0vlib9WcwlxXlpqSMDn3fH/0, createdBy=94c32116583, createdName=Susanheee, createdTime=Mon Oct 22 10:13:02 CST 2018, time=2018-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718365, encodeId=dd481e1836552, content=<a href='/topic/show?id=5ce04315043' target=_blank style='color:#2F92EE;'>#多囊卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43150, encryptionId=5ce04315043, topicName=多囊卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c91632558486, createdName=kalseyzl, createdTime=Wed Dec 23 05:47:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=64477, encodeId=399a644e700, content=和激素水平有关?, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/14/d0501100fdfe783cab0715811e01c133.jpg, createdBy=51ed1602754, createdName=mengli1984, createdTime=Tue Feb 16 20:23:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61688, encodeId=8b5961688bf, content=有干预措施吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Jan 28 02:26:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58493, encodeId=880058493ca, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Jan 20 09:31:00 CST 2016, time=2016-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430564, encodeId=316c143056438, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527597, encodeId=b087152e597f4, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45461, encodeId=5a68454619d, content=高雄, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 10 14:16:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-10 xiongke014
  8. [GetPortalCommentsPageByObjectIdResponse(id=350141, encodeId=1f3a35014173, content=儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZib5pXwccy19pABmFn91nGEwyWbA7qibiaOHVwhzltCSm8rkUSTM3QNkuj0vlib9WcwlxXlpqSMDn3fH/0, createdBy=94c32116583, createdName=Susanheee, createdTime=Mon Oct 22 10:13:02 CST 2018, time=2018-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718365, encodeId=dd481e1836552, content=<a href='/topic/show?id=5ce04315043' target=_blank style='color:#2F92EE;'>#多囊卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43150, encryptionId=5ce04315043, topicName=多囊卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c91632558486, createdName=kalseyzl, createdTime=Wed Dec 23 05:47:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=64477, encodeId=399a644e700, content=和激素水平有关?, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/14/d0501100fdfe783cab0715811e01c133.jpg, createdBy=51ed1602754, createdName=mengli1984, createdTime=Tue Feb 16 20:23:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61688, encodeId=8b5961688bf, content=有干预措施吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Jan 28 02:26:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58493, encodeId=880058493ca, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Jan 20 09:31:00 CST 2016, time=2016-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430564, encodeId=316c143056438, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527597, encodeId=b087152e597f4, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45461, encodeId=5a68454619d, content=高雄, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 10 14:16:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-10 liuxiaona
  9. [GetPortalCommentsPageByObjectIdResponse(id=350141, encodeId=1f3a35014173, content=儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZib5pXwccy19pABmFn91nGEwyWbA7qibiaOHVwhzltCSm8rkUSTM3QNkuj0vlib9WcwlxXlpqSMDn3fH/0, createdBy=94c32116583, createdName=Susanheee, createdTime=Mon Oct 22 10:13:02 CST 2018, time=2018-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718365, encodeId=dd481e1836552, content=<a href='/topic/show?id=5ce04315043' target=_blank style='color:#2F92EE;'>#多囊卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43150, encryptionId=5ce04315043, topicName=多囊卵巢)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c91632558486, createdName=kalseyzl, createdTime=Wed Dec 23 05:47:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=64477, encodeId=399a644e700, content=和激素水平有关?, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/14/d0501100fdfe783cab0715811e01c133.jpg, createdBy=51ed1602754, createdName=mengli1984, createdTime=Tue Feb 16 20:23:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61688, encodeId=8b5961688bf, content=有干预措施吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Jan 28 02:26:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58493, encodeId=880058493ca, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Jan 20 09:31:00 CST 2016, time=2016-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430564, encodeId=316c143056438, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527597, encodeId=b087152e597f4, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561574, encodeId=73e515615e454, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567583, encodeId=e7fd156e5837c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu Dec 10 15:47:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45461, encodeId=5a68454619d, content=高雄, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 10 14:16:00 CST 2015, time=2015-12-10, status=1, ipAttribution=)]
    2015-12-10 liuxiaona
  10. [GetPortalCommentsPageByObjectIdResponse(id=350141, encodeId=1f3a35014173, content=儿童在胎儿时期过早暴露于性激素(雄激素)下,可能是导致患自闭症的重要因素, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZib5pXwccy19pABmFn91nGEwyWbA7qibiaOHVwhzltCSm8rkUSTM3QNkuj0vlib9WcwlxXlpqSMDn3fH/0, createdBy=94c32116583, createdName=Susanheee, createdTime=Mon Oct 22 10:13:02 CST 2018, time=2018-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718365, encodeId=dd481e1836552, content=<a href='/topic/show?id=5ce04315043' target=_blank style='color:#2F92EE;'>#多囊卵巢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43150, encryptionId=5ce04315043, topicName=多囊卵巢)], attachment=null, authenticateStatus=null, 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    2015-12-10 lpapple

    高雄

    0

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