Neurology:青少年急性缺血性卒中

2019-12-13 xing.T MedSci原创

由此可见,青少年的缺血性卒中强调在治疗中需要多学科协作,再通治疗似乎可行且安全。

青春期是儿童到成年之间的过渡期,关于这一人群卒中特征的信息很少。近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员旨在描述青少年缺血性卒中的临床和神经影像学特征、病因、初步治疗和结果。

这项回顾性队列研究评估了2007年至2017年期间住院的10至18岁的首次缺血性卒中患者。该研究是在10个法国学术中心中进行,人口约1000万。研究人员从国家数据库中提取数据作为验证。

该研究共纳入了60例患者(男性占53%,中位年龄为15.2岁)。初次就诊时的误诊为36%,后循环卒中比前循环卒中更常见(分别为55%和20%,比值比为4.8,95%置信区间为1.41-16.40,p=0.01)。再通治疗率很高(n=19,32%):静脉溶栓(17%)、血管内治疗(11.7%)或静脉和动脉内溶栓(3.3%);安全性良好(仅1例无症状出血性转化患者)。尽管进行了彻底的病因检查,但仍有50%的卒中是隐源性的。明确的最常见病因为心脏栓塞(15%)、血管炎和自身免疫性疾病(12%,仅在女性患者中发生)和动脉夹层(10%,仅在男性患者中发生)。复发性缺血性脑血管事件发生率为12%(中位随访19个月)。可识别出的血管病患者复发率为50%,而隐源性卒中后的复发率为0%。在80%的病例中,功能预后良好(Rankin量表评分为0–2)。

由此可见,青少年的缺血性卒中强调在治疗中需要多学科协作,再通治疗似乎可行且安全。 

原始出处:

Thomas Rambaud,et al.Acute ischemic stroke in adolescents.Neurology.2019. https://doi.org/10.1212/WNL.0000000000008783

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1806364, encodeId=080e1806364d0, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Apr 07 05:52:00 CST 2020, time=2020-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000933, encodeId=bdba20009339c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Mon Nov 16 03:52:00 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893241, encodeId=ef571893241f7, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Sun Mar 01 01:52:00 CST 2020, time=2020-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026513, encodeId=db00102651395, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Dec 14 00:52:00 CST 2019, time=2019-12-14, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1806364, encodeId=080e1806364d0, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Apr 07 05:52:00 CST 2020, time=2020-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000933, encodeId=bdba20009339c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Mon Nov 16 03:52:00 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893241, encodeId=ef571893241f7, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Sun Mar 01 01:52:00 CST 2020, time=2020-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026513, encodeId=db00102651395, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Dec 14 00:52:00 CST 2019, time=2019-12-14, status=1, ipAttribution=)]
    2020-11-16 hb2008ye
  3. [GetPortalCommentsPageByObjectIdResponse(id=1806364, encodeId=080e1806364d0, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Apr 07 05:52:00 CST 2020, time=2020-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000933, encodeId=bdba20009339c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Mon Nov 16 03:52:00 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893241, encodeId=ef571893241f7, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Sun Mar 01 01:52:00 CST 2020, time=2020-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026513, encodeId=db00102651395, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Dec 14 00:52:00 CST 2019, time=2019-12-14, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1806364, encodeId=080e1806364d0, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Apr 07 05:52:00 CST 2020, time=2020-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000933, encodeId=bdba20009339c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Mon Nov 16 03:52:00 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893241, encodeId=ef571893241f7, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Sun Mar 01 01:52:00 CST 2020, time=2020-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026513, encodeId=db00102651395, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Dec 14 00:52:00 CST 2019, time=2019-12-14, status=1, ipAttribution=)]
    2019-12-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

相关资讯

Int J Pediatr Otorhinolaryngol:韩国青少年听力损失的患病率和临床表现群体研究

轻度听力损失对交流和学术成就具有不良的影响。最近,有研究人员描述了听力损失的患病率,并调查了与噪音诱导的听力损失相关的因子。研究是一个基于群体的研究,包括了1845名年龄在12岁到19岁的青少年,数据来源于韩国国家健康和营养调查V数据库(KNHANES V, 2010-2012)。研究人员根据位置、严重度和频率推算了听力损失的患病率。为了评估青少年中噪音诱导的听力损失,研究人员分析了≤15dB H

Pediatric Diabetes:青少年人群的糖尿病类型不同,抑郁症状也有所不同?

既往曾有研究显示,糖尿病与抑郁密切相关。那么,在青少年人群中,糖尿病与抑郁的关系如何?糖尿病类型对两者的关系又有何影响?近期,美国斯坦福大学医学院的Jessie J. Wong等人专门就此问题进行了相应研究。

Hypertension:移民对青少年的BMI和血压的影响

从一种文化环境移民到另一种文化环境的成年人发生心血管代谢性疾病的风险增加。但移民对青少年身体健康的影响尚无明确数据。研究人员在以色列开展一项全国性、人口为基础的横向研究,根据1992年-2016年的记录数据评估原籍为埃塞俄比亚的移民青少年(16-19岁)的体重指数(BMI)和血压水平,以及他们的超重和肥胖的长期趋势。根据出生地将受试者分为以色列出生的(16 153人)和移民的(23 487人),并

JAMA:2019美国青少年电子烟流行率研究

研究发现,2019年,美国高中生和中学生自述电子烟使用率很高,大多数青少年吸烟人群使用调味电子烟

JCEM:超重和肥胖对儿童和青少年肝脏生化指标的影响

由此可见,小儿肝酶正常值随年龄和性别而变化。超重和肥胖与肝脏损害的生化指标升高有关。这些发现强调了预防和治疗儿童和青少年超重和肥胖的必要性。

NEJM:青少年皮肌炎钙化病-病例报道

考虑到患者顽固性青少年皮肌炎和严重的钙化病,开始使用英夫利昔单抗、沙利度胺和氢氧化铝治疗。治疗后两个月,患者的肌肉力量和皮疹褪色有所改善。