Stroke:大脑中动脉高斑块负担与反复缺血性卒中相关

2019-12-23 xing.T MedSci原创

由此可见,在磁共振血管壁成像上发现的大脑中动脉较高的斑块负担与复发性缺血性卒中独立相关。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,该研究旨在利用磁共振血管壁成像技术探究大脑中动脉粥样硬化斑块的特征与复发性缺血性卒中之间的关系。

一百零五例归因于大脑中动脉斑块的缺血性卒中患者接受了高分辨率的黑血序列磁共振血管壁成像检查。他们被分为第1组,首次急性卒中(在卒中4周内成像,n=44);第2组,复发性急性卒中(n=29);第3组为慢性卒中(卒中3个月后成像检查,n=32)。研究人员测量并比较了3组患者的斑块特征,包括斑块面积、斑块负担、对比增强比、离心率和狭窄程度。研究人员通过多变量分析探究斑块特征与复发性卒中之间的关联。

复发性卒中组的斑块负担明显高于其他两组(中位数:第2组为82.7%,而第1组为76.3%,第3组为73.4%; P=0.001)。急性卒中患者比慢性卒中患者具有更高的增强率(中位数:第1组为1.59;第2组为1.90;而第3组为1.33;P=0.014)。与首次发作的急性卒中患者相比,复发性卒中患者年龄更大,女性和高血压的可能性更高,并且斑块负担更高。在调整了临床因素后,斑块负担是与卒中复发相关的唯一独立影像学特征(比值比为2.26,每增加10%比值比为2.26[95%CI为1.03-4.96];P=0.042)。

由此可见,在磁共振血管壁成像上发现的大脑中动脉较高的斑块负担与复发性缺血性卒中独立相关。

原始出处:


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    2019-12-24 yjs木玉

    好好好好好好

    0

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  9. [GetPortalCommentsPageByObjectIdResponse(id=1634453, encodeId=72ea1634453b5, content=<a href='/topic/show?id=e6084385876' target=_blank style='color:#2F92EE;'>#大脑中动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43858, encryptionId=e6084385876, topicName=大脑中动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=376422174069, createdName=楚钟, createdTime=Fri May 08 00:41:00 CST 2020, time=2020-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076535, encodeId=789020e6535fb, content=<a href='/topic/show?id=36e6438643a' target=_blank style='color:#2F92EE;'>#大脑中动脉高斑块负担#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43864, encryptionId=36e6438643a, topicName=大脑中动脉高斑块负担)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Sep 07 21:41:00 CST 2020, time=2020-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893242, encodeId=ff0c1893242e7, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Dec 26 07:41:00 CST 2019, time=2019-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806365, encodeId=cdb01806365ae, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Jul 24 12:41:00 CST 2020, time=2020-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330133, encodeId=13d013301339a, content=<a href='/topic/show?id=a91c5e92328' target=_blank style='color:#2F92EE;'>#斑块#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57923, encryptionId=a91c5e92328, topicName=斑块)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Wed Dec 25 13:41:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625778, encodeId=7f631625e780a, content=<a href='/topic/show?id=1ada3e70777' target=_blank style='color:#2F92EE;'>#反复缺血性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37707, encryptionId=1ada3e70777, topicName=反复缺血性卒中)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307a20894576, createdName=yangshch, createdTime=Wed Dec 25 13:41:00 CST 2019, time=2019-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377358, encodeId=20863e7358a5, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Tue Dec 24 07:10:02 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377353, encodeId=d2f63e73531d, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d551998554, createdName=1e1c07bdm01(暂无匿称), createdTime=Tue Dec 24 06:47:29 CST 2019, time=2019-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026520, encodeId=a5cb10265209f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Dec 24 01:41:00 CST 2019, time=2019-12-24, status=1, ipAttribution=)]
    2019-12-24 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0