Communications Biology:一天睡7个小时对执行功能和大脑结构理想

2022-03-06 影像小生 MedSci原创

强调了睡眠持续时间与认知之间的重要关系,以及睡眠与结构性大脑健康之间的广泛关联。

睡眠对日常生活至关重要,在一系列生理功能中起着重要作用。睡眠对大脑的影响尤其巨大,更好地理解这一点可能会在人们随着年龄增长而保持健康的认知老化中发挥关键作用。然而,关于睡眠和大脑健康的关键问题仍然存在。

提出科学问题①对认知功能来说,最佳的睡眠时间是多少?②这在人的一生中会发生变化吗?③睡眠与大脑结构健康有什么关系

Xin You Tai等在Communications Biology杂志发表题为Impact of sleep duration on executive function and brain structure的研究文章,调查研究了38岁-73岁的479,420名健康个体的睡眠时间和认知表现之间的关系,同时考虑了社会经济因素、心血管和遗传风险的影响。还在一个由37,898名参加多模态脑成像的人组成的亚组中探索了睡眠与脑容量之间的关系。

该团队检查了来自英国生物银行 ( N = 479,420) 的中晚期健康个体(年龄 38-73 岁)的睡眠和认知数据,以及一个亚组( N = 37,553)与大脑结构的关系。

年龄、睡眠时长和执行功能的关系

每天七小时的睡眠与最高的认知能力有关,低于和高于这个睡眠时间的每一小时都会下降。这种二次方程关系在老年人中仍然存在(>60 岁,N= 212,006)

睡眠时间在 6 到 8 小时之间的个体在 139 个不同的大脑区域中的 46 个区域的灰质体积显着增加,包括眶额皮质、海马、中央前回、右额极和小脑亚区。

与其他睡眠时间长的人相比,睡眠时间在6 - 8小时的人的大脑区域体积更大

白质高信号负荷与睡眠持续时间、睡眠轨迹;睡眠时长、脑体积和执行功能之间的关系。

几个大脑区域在睡眠时间和体积之间显示出二次方程关系。

该研究结果为睡眠和广泛的大脑结构网络的完整性之间的关系提供了见解,也证明了睡眠时间这一可改变的生活方式因素是如何与认知表现相关的,这对中老年个体保持健康认知老化的日常生活习惯有影响。

原文出处

Tai, X.Y., Chen, C., Manohar, S. et al. Impact of sleep duration on executive function and brain structure. Commun Biol 5, 201 (2022). https://doi.org/10.1038/s42003-022-03123-3

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    2022-06-10 liuli5079
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    2022-04-12 sunylz
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    2022-03-11 yx1156

    高质量的睡眠就好!

    0

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    2022-03-08 wmr116
  7. [GetPortalCommentsPageByObjectIdResponse(id=1767899, encodeId=25401e67899f6, content=<a href='/topic/show?id=64f5343e2f' target=_blank style='color:#2F92EE;'>#Biol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3437, encryptionId=64f5343e2f, topicName=Biol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Sat Oct 01 16:02:23 CST 2022, time=2022-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2088144, encodeId=e3d22088144b6, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Fri Jun 10 03:02:23 CST 2022, time=2022-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1919402, encodeId=efd4191940269, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Tue Apr 12 13:02:23 CST 2022, time=2022-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1201598, encodeId=603a1201598a8, content=高质量的睡眠就好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58001397990, createdName=yx1156, createdTime=Fri Mar 11 04:27:22 CST 2022, time=2022-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424045, encodeId=df2814240458c, content=<a href='/topic/show?id=34db439533f' target=_blank style='color:#2F92EE;'>#大脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43953, encryptionId=34db439533f, topicName=大脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d9a3889985, createdName=shanyongle, createdTime=Tue Mar 08 03:02:23 CST 2022, time=2022-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556540, encodeId=973115565405c, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Tue Mar 08 03:02:23 CST 2022, time=2022-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1200111, encodeId=0bff120011159, content=今天不够, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da196447565, createdName=4nfu, createdTime=Mon Mar 07 06:42:55 CST 2022, time=2022-03-07, status=1, ipAttribution=)]
    2022-03-07 4nfu

    今天不够

    0

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