Eur Respir J:年轻人慢性支气管炎和危险因素评估

2020-11-13 MedSci原创 MedSci原创

年轻人慢性支气管炎与反复呼吸道感染有关。除吸烟外,该研究结果还支持早期生活中暴露的影响,例如空气污染和纯母乳喂养,这对以后的呼吸健康具有重要作用。

慢性支气管炎与老年人较高的发病率有关,但对于年轻人患病率和危险因素知之甚少。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,研究人员旨在评估年轻人慢性支气管炎的患病率和早期生命危险因素。

研究人员使用瑞典BAMSE队列24年随访的问卷调查数据和临床指标,通过冬季早晨的咳嗽合并粘液产生来评估慢性支气管炎(CB)。从出生到以后的环境和临床数据都用于分析危险因素。

在24年的随访中,75%(n=3064)的参与者完成了调查问卷,并于2030年进行了肺活量测定。男性的总体患病率为5.5%(n=158),男性和女性相似。去年,49%的CB病例经历了超过3次自我报告的呼吸道感染,相比之下,非CB受试者为18%(p<0.001),并且37%的患者为当前吸烟者(相对于19%)。与非CB受试者相比,在CB受试者中观察到FEV1/FVC显著性降低(z平均值为-0.06 vs. 0.13,p=0.027)。每日吸烟(调整后的几率,aOR=3.85,p<0.001)、空气污染暴露(1-4岁年龄段暴露于黑碳每增加1μg·m3,aOR=1.71,p=0.009),并且在此期间仅母乳喂养四个月或更长时间(aOR=0.66,p=0.044)与CB相关。

由此可见,年轻人慢性支气管炎与反复呼吸道感染有关。除吸烟外,该研究结果还支持早期生活中暴露的影响,例如空气污染和纯母乳喂养,这对以后的呼吸健康具有重要作用。

原始出处:

Gang Wang,et al.Assessment of chronic bronchitis and risk factors in young adults: Results from BAMSE.Eur Respir J.2020.https://erj.ersjournals.com/content/early/2020/09/17/13993003.02120-2020

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    2020-11-27 jacob9231

    学习了谢谢

    0

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likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Sat Nov 21 21:14:32 CST 2020, time=2020-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900818, encodeId=cd629008180c, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Fri Nov 20 15:47:41 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900537, encodeId=6cc190053eb2, content=<a href='/topic/show?id=04e853528ee' target=_blank style='color:#2F92EE;'>#慢性支气管炎#</a> <a href='/topic/show?id=3c2c3968817' target=_blank style='color:#2F92EE;'>#呼吸系统#</a> <a href='/topic/show?id=bc4f39e1748' target=_blank style='color:#2F92EE;'>#呼吸道感染#</a> 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53528, encryptionId=04e853528ee, topicName=慢性支气管炎), TopicDto(id=39688, encryptionId=3c2c3968817, topicName=呼吸系统), TopicDto(id=39717, encryptionId=bc4f39e1748, topicName=呼吸道感染)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Thu Nov 19 17:23:30 CST 2020, time=2020-11-19, status=1, ipAttribution=)]
    2020-11-26 jacob9231

    学习了谢谢

    0

  4. 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    2020-11-25 jacob9231

    学习了谢谢

    0

  5. 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    2020-11-25 14838411m74暂无昵称

    学习了

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Tue Nov 24 23:38:12 CST 2020, time=2020-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=901310, encodeId=4afd901310dd, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Nov 23 00:01:37 CST 2020, time=2020-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=901054, encodeId=2fc4901054db, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Sat Nov 21 21:14:32 CST 2020, time=2020-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900818, encodeId=cd629008180c, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Fri Nov 20 15:47:41 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900537, encodeId=6cc190053eb2, content=<a href='/topic/show?id=04e853528ee' target=_blank style='color:#2F92EE;'>#慢性支气管炎#</a> <a href='/topic/show?id=3c2c3968817' target=_blank style='color:#2F92EE;'>#呼吸系统#</a> <a href='/topic/show?id=bc4f39e1748' target=_blank style='color:#2F92EE;'>#呼吸道感染#</a> 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53528, encryptionId=04e853528ee, topicName=慢性支气管炎), TopicDto(id=39688, encryptionId=3c2c3968817, topicName=呼吸系统), TopicDto(id=39717, encryptionId=bc4f39e1748, topicName=呼吸道感染)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Thu Nov 19 17:23:30 CST 2020, time=2020-11-19, status=1, ipAttribution=)]
    2020-11-24 jacob9231

    学习了谢谢

    0

  7. 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    2020-11-23 jacob9231

    学习了谢谢

    0

  8. 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likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Sat Nov 21 21:14:32 CST 2020, time=2020-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900818, encodeId=cd629008180c, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Fri Nov 20 15:47:41 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900537, encodeId=6cc190053eb2, content=<a href='/topic/show?id=04e853528ee' target=_blank style='color:#2F92EE;'>#慢性支气管炎#</a> <a href='/topic/show?id=3c2c3968817' target=_blank style='color:#2F92EE;'>#呼吸系统#</a> <a href='/topic/show?id=bc4f39e1748' target=_blank style='color:#2F92EE;'>#呼吸道感染#</a> 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53528, encryptionId=04e853528ee, topicName=慢性支气管炎), TopicDto(id=39688, encryptionId=3c2c3968817, topicName=呼吸系统), TopicDto(id=39717, encryptionId=bc4f39e1748, topicName=呼吸道感染)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Thu Nov 19 17:23:30 CST 2020, time=2020-11-19, status=1, 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    2020-11-21 jacob9231

    学习了谢谢

    0

  9. 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GetPortalCommentsPageByObjectIdResponse(id=900537, encodeId=6cc190053eb2, content=<a href='/topic/show?id=04e853528ee' target=_blank style='color:#2F92EE;'>#慢性支气管炎#</a> <a href='/topic/show?id=3c2c3968817' target=_blank style='color:#2F92EE;'>#呼吸系统#</a> <a href='/topic/show?id=bc4f39e1748' target=_blank style='color:#2F92EE;'>#呼吸道感染#</a> 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53528, encryptionId=04e853528ee, topicName=慢性支气管炎), TopicDto(id=39688, encryptionId=3c2c3968817, topicName=呼吸系统), TopicDto(id=39717, encryptionId=bc4f39e1748, topicName=呼吸道感染)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Thu Nov 19 17:23:30 CST 2020, time=2020-11-19, status=1, ipAttribution=)]
    2020-11-20 jacob9231

    学习了谢谢

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=900537, encodeId=6cc190053eb2, content=<a href='/topic/show?id=04e853528ee' target=_blank style='color:#2F92EE;'>#慢性支气管炎#</a> <a href='/topic/show?id=3c2c3968817' target=_blank style='color:#2F92EE;'>#呼吸系统#</a> <a href='/topic/show?id=bc4f39e1748' target=_blank style='color:#2F92EE;'>#呼吸道感染#</a> 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53528, encryptionId=04e853528ee, topicName=慢性支气管炎), TopicDto(id=39688, encryptionId=3c2c3968817, topicName=呼吸系统), TopicDto(id=39717, encryptionId=bc4f39e1748, topicName=呼吸道感染)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/a16c22989a2247c0a54b44d3e3acdaaa/44abb281938b4e04bc086f8345254626.jpg, createdBy=fb825296401, createdName=BJying, createdTime=Thu Nov 19 17:23:30 CST 2020, time=2020-11-19, status=1, ipAttribution=)]
    2020-11-19 BJying

    #慢性支气管炎# #呼吸系统# #呼吸道感染# 研究结果还支持早期生活中暴露的影响,其中包括母乳喂养,而这也是其他研究中比较容易忽略的暴露因素。

    0

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