Am J Clin Nutr:中国人长期饮食质量与肠道菌群多样性的相关性

2021-01-22 MedSci原创 MedSci原创

肠道菌群已被认为是人类生理学许多方面的重要贡献者,从营养和代谢到免疫反应和神经行为特征。然而,目前很少有基于人群的评估长期饮食对肠道菌群的影响的研究,也缺乏亚洲人群的相关数据。

肠道菌群已被认为是人类生理学许多方面的重要贡献者,从营养和代谢到免疫反应和神经行为特征。然而,目前很少有基于人群的评估长期饮食对肠道菌群的影响的研究,也缺乏亚洲人群的相关数据。

近日,发表在《美国临床营养学杂志》上的一项来自中国学者的研究,评估了中国成年人长期饮食质量(包括水果、蔬菜、乳制品、鱼/海鲜、坚果/豆类、精制谷物、红肉和加工肉)与肠道菌群的关系

该研究纳入了1920位受试者。1996-2006年,受试者在大便收集时没有血管疾病、糖尿病和癌症(2015-2018年),且在大便收集前7天内没有腹泻或使用抗生素。通过16S rRNA测序对菌群进行分析。长期饮食通过基线和随访(1996-2011年)过程中的重复调查进行评估,饮食调查和粪便收集之间的间隔为5.2-20.5年。

大便采集时的平均年龄为68±1.5岁,饮食质量与微生物群α多样性和厚壁菌、放线菌、软壁菌、副球菌、费氏杆菌/普氏杆菌、双歧杆菌等的丰度呈正相关。乳制品、鱼/海鲜、坚果/豆类、精制谷物和加工肉类的摄入量也与肠道菌群存在显著的相关性,如乳制品的摄入量与双歧杆菌的丰度呈正相关,加工肉类与粪便罗斯氏菌呈负相关。除了既往6个月应用过抗生素以外,有没有根据体重指数和高血压状态进行调整,大多数相关性基本相似。

综上,在看似健康的中国成年人中,长期饮食质量与粪便微生物群多样性和纤维发酵菌丰度呈正相关。未来需要进一步检验这些细菌是否可能调节或改变饮食与疾病的关系。

原始出处:

Danxia Yu, et al. Long-term diet quality is associated with gut microbiome diversity and composition among urban Chinese adults. The American Journal of Clinical Nutrition. 20 January 2021

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    2021-01-22 lifefamily

    #饮食#质量与#肠道菌群#多样性,可以这样说,人的饮食,#情绪#,甚至#运动#都可以导致#肠道微生物##可塑性#,时间长了,则会影响人体全方位的功能

    0

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