Pediatrics:无症状先天性巨细胞病毒感染的前庭、凝视和平衡障碍

2021-01-24 AlexYang MedSci原创

先天性巨细胞病毒(cCMV)是感音神经性听力损失和发育障碍的主要非遗传性病因。由于在选定的cCMV患儿群体中,前庭受累的研究数据有限,cCMV前庭障碍的真实频率可能被低估。最近,研究人员确定了无症状c

先天性巨细胞病毒(cCMV)是感音神经性听力损失和发育障碍的主要非遗传性病因。由于在选定的cCMV患儿群体中,前庭受累的研究数据有限,cCMV前庭障碍的真实频率可能被低估。最近,研究人员确定了无症状cCMV儿童队列中前庭、凝视和平衡障碍的患病率

研究人员在40名无症状cCMV患儿中进行了全面的前庭、凝视和平衡评估;并将每个变量的测试结果与没有CCMV的对照组和/或与年龄匹配的标准公布数据进行了比较。结果表明,根据旋转椅和颈部前庭诱发肌源性电位测试结果,研究队列的45%的受试者前庭障碍明显,表明半规管、内耳的椭圆囊和球囊以及前庭视束存在异常。此外,46%的受试者在头部运动时难以维持凝视,三分之一至二分之一的受试者难以维持平衡。

最后,研究人员指出,前庭、凝视和平衡障碍在无症状的CCMV患儿中高度流行。前庭障碍的系统筛查可用于确定整体的临床影响,从而制定有效的干预措施。

原始出处:

Swetha Pinninti , Jennifer Christy , Anwar Almutairi et al. Vestibular, Gaze, and Balance Disorders in Asymptomatic Congenital Cytomegalovirus Infection. Pediatrics. Jan 2021

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    2021-12-15 feather89
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    2021-12-26 hbwxf
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    2021-01-26 huirong
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    2021-01-26 wwzzly

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