JAHA:轻至中度卒中后一年内抑郁症患病率和病程分析

2021-06-29 MedSci原创 MedSci原创

该研究观察到了卒中后抑郁症状的动态改变表明,在轻度至中度卒中患者中,卒中后抑郁往往在6个月后仍然持续存在,应持续监测和适当管理。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在调查轻度至中度卒中后第一年内抑郁症的患病率和纵向病程变化。

研究人员确定了轻度至中度缺血性卒中或脑出血患者(美国国立卫生研究院卒中量表评分<16),并且在卒中后 3、6或12个月时至少进行了1次抑郁评估(分别为n=648、542和533) 。潜在转变分析用于评估卒中后3至12个月期间由8项患者健康问卷衡量的抑郁症状特征。

该研究参与者的平均年龄为65.6岁,49.4%为女性,56.7%为墨西哥裔美国人。卒中后抑郁的患病率在3个月时为35.3%,在6个月时降至24.9%,并在12个月时保持稳定为25.7%。大约一半在3或6个月时被归类为患有抑郁症的参与者在下一次评估发生临床改善。

卒中后3、6和12月抑郁症状患病率

研究人员确定了具有不同抑郁症状模式的亚组,包括轻度/无症状、主要的睡眠障碍和疲劳症状、情感症状和严重/所有症状。大多数有轻微/无症状的参与者随着时间的推移这种症状仍然持续。卒中后前6个月转为轻度/无症状的概率高于后期,卒中6个月后重度症状持续的可能性高于前期。
 
由此可见,该研究观察到了卒中后抑郁症状的动态改变表明,在轻度至中度卒中患者中,卒中后抑郁往往在6个月后仍然持续存在,应持续监测和适当管理
 
原始出处:

Liming Dong.et al.Prevalence and Course of Depression During the First Year After Mild to Moderate Stroke.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.020494

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    2021-07-01 zhaohui6731
  4. [GetPortalCommentsPageByObjectIdResponse(id=1671432, encodeId=b16616e14323f, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Oct 05 16:27:08 CST 2021, time=2021-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250744, encodeId=0d821250e4431, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Thu Jul 01 14:27:08 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268572, encodeId=6c4c12685e209, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Thu Jul 01 14:27:08 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026892, encodeId=6f7e1026892c6, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Wed Jun 30 02:27:08 CST 2021, time=2021-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978071, encodeId=3fef9e807149, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Tue Jun 29 23:47:27 CST 2021, time=2021-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978067, encodeId=6a4b9e806747, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210629/fd8bb0501cf445f08b618077b6c433bd/6ab9b249881c4d9da9867eb687e3a5a9.jpg, createdBy=10725529570, createdName=ms8000001817907749, createdTime=Tue Jun 29 23:39:57 CST 2021, time=2021-06-29, status=1, ipAttribution=)]
    2021-06-30 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2021-06-29 452946589

    学习了

    0

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    2021-06-29 ms8000001817907749

    0

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